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Proteins/UNIPROT:O60711
Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling..
Function from UniProtKB (O60711), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
118 statements
118 statements · 2 reference databases · Subject: LPXN · Sources: gene ontology, Hetionet
2 names
Resolves to: LPXN