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Proteins/UNIPROT:P17301
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A..
(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8..
Function from UniProtKB (P17301), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
255 statements
255 statements · 4 reference databases · Subject: ITGA2 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
7 names
Resolves to: ITGA2