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Proteins/UNIPROT:P78330
Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine (Probable)..
Function from UniProtKB (P78330), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
169 statements
169 statements · 5 reference databases · Subject: PSPH · Sources: Hetionet, Reactome, Rhea, UniProt, WikiPathways
3 reactions
MAM00916c+waterphosphate(3-)+L-seryl residue
Catalysed by PSPH
Reaction pageLeft to rightBalancedEC 3.1.3.3cytosol
Human-GEM MAR03843CC BY 4.0Reference data
CHEBI:57524+waterL-seryl residue+hydrogenphosphate
Catalysed by PSPH
Reaction pageLeft to rightBalanced
Rhea RHEA:21208CC BY 4.0Reference data
4 names
Resolves to: PSPH
O-phospho-D-serine+waterD-serine+hydrogenphosphate
Catalysed by PSPH
Reaction pageLeft to rightBalanced
Rhea RHEA:24873CC BY 4.0Reference data