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Proteins/UNIPROT:Q9NPJ3
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (By similarity). Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro) (By similarity). May play a role in controlling adaptive thermogenesis (By similarity)..
Function from UniProtKB (Q9NPJ3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
102 statements
102 statements · 8 reference databases · Subject: ACOT13 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
37 reactions
water+dodecanoyl-CoACHEBI:1146900+proton+dodecanoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00189CC BY 4.0Reference data
water+MAM03050cCHEBI:1146900+proton+
6 names
Resolves to: ACOT13
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00193CC BY 4.0Reference data
water+tetradecanoyl-CoACHEBI:1146900+proton+tetradecanoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00197CC BY 4.0Reference data
MAM00129c+waterMAM00128c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00201CC BY 4.0Reference data
(7Z)-tetradecenoyl-CoA+waterMAM00117c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00206CC BY 4.0Reference data
water+MAM02689cCHEBI:1146900+proton+MAM02690c
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00214CC BY 4.0Reference data
water+palmitoyl-CoACHEBI:1146900+proton+hexadecanoic acid
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00223CC BY 4.0Reference data
water+(9Z)-hexadecenoyl-CoACHEBI:1146900+proton+(9Z)-hexadecenoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00230CC BY 4.0Reference data
(7Z)-hexadecenoyl-CoA+waterMAM01197c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00234CC BY 4.0Reference data
water+heptadecanoyl-CoACHEBI:1146900+proton+MAM02456c
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00238CC BY 4.0Reference data
(9Z)-heptadecenoyl-CoA+waterMAM01238c+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00246CC BY 4.0Reference data
water+octadecanoyl-CoACHEBI:1146900+proton+octadecanoate
Catalysed by ACOT1 or ACOT7 or BAAT or ACOT13 or THEM4
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00250CC BY 4.0Reference data