(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA

1. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase

Catalysed by BAAT, ACOT6, ACOT1cytosolOne of 10 routes

1. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-eicosahexaenoyl-CoA + H2O2

Catalysed by ACOX1

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase

Catalysed by BAAT, ACOT6, ACOT1cytosolOne of 2 routes

1. Beta Oxidation of Fatty Acid

Catalysed by ACADM, ACADSmitochondrial matrixOne of 2 routes

1. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + CO2 + CoA

Catalysed by ELOVL2, ELOVL5

1. fatty-acyl-CoA elongation (N-C20:5CoA)

Catalysed by ELOVL4, ELOVL6, ELOVL2, ELOVL5cytosol

1. Acyl-CoA:cholesterol O-acyltransferase

Catalysed by SOAT2, SOAT1endoplasmic reticulumOne of 2 routes

1. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by BAAT, ACOT6, ACOT1, CPT1A and 2 morecytosolOne of 244 routes

1. Acyl-CoA:cholesterol O-acyltransferase
2. Steryl-ester acylhydrolase

Catalysed by SOAT2, SOAT1, CEL, LIPAendoplasmic reticulum, lysosome