(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

242 compounds within 3 steps: 3 in 1, 37 in 2, 202 in 3

One step

CHEBI:1307929Reach from here →
1. Steryl-ester acylhydrolase
Catalysed by CEL, LIPAlysosomeOne of 3 routes
a cholesterol esterReach from here →
1. cholesterol-ester plasma pool to cholesterol-ester-10,13,16,19-docosa conversion
No catalyst recordedendoplasmic reticulumOne of 3 routes
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →
1. Steryl-ester acylhydrolase
Catalysed by CEL, LIPAlysosomeOne of 3 routes

Two steps

CHEBI:1146900Reach from here →
1. Steryl-ester acylhydrolase
2. Sterol O-Acyltransferase
Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 60 routes
(22S)-22-hydroxycholesterolReach from here →
1. Steryl-ester acylhydrolase
2. cytochrome P450 (cholesterol)
Catalysed by CEL, LIPA, CYP11A1, CYP1B1lysosome, mitochondrial matrix

Three steps

(S)-carnitineReach from here →
Catalysed by CEL, LIPA, SOAT2, SOAT1 and 3 morelysosome, endoplasmic reticulum, cytosolOne of 244 routes
(20R,22R)-20,22-dihydroxycholesterolReach from here →

AReach from here →

Catalysed by CEL, LIPA, PTGS2lysosomeOne of 5 routes

(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

prostaglandin G3Reach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoateReach from here →

Catalysed by CEL, LIPA, CYP2C9lysosome

11,12-epoxy-(5Z,8Z,14Z,17Z)-eicosatetraenoateReach from here →

Catalysed by CEL, LIPA, CYP2C8, CYP2C9lysosome

14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoateReach from here →

Catalysed by CEL, LIPA, CYP2C8, CYP2C9lysosome

cholesterol sulfateReach from here →

Catalysed by CEL, LIPA, SULT2B1, SULT1A3lysosome, cytosolOne of 3 routes

cholesterolReach from here →

Catalysed by CES1, LIPN, NCEH1, LDAHendoplasmic reticulum

pregnenoloneReach from here →

Catalysed by CEL, LIPA, CYP11A1lysosome, mitochondrial matrix

7alpha-hydroxycholesterolReach from here →

Catalysed by CEL, LIPA, CYP7A1lysosome, endoplasmic reticulum

1-O-acyl-sn-glycero-3-phosphocholine(1+)Reach from here →

Catalysed by CEL, LIPA, LCATlysosome, cytosolOne of 2 routes

desmosterolReach from here →

Catalysed by CEL, LIPAlysosome, nucleus

4-methylpentanalReach from here →

Catalysed by CEL, LIPA, CYP11A1lysosome, mitochondrial matrix

(5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, ALOX5lysosome

a fatty acidReach from here →

Catalysed by CES1, LIPN, NCEH1, LDAHendoplasmic reticulum

(24S)-hydroxycholesterolReach from here →

Catalysed by CEL, LIPA, CYP46A1lysosome, endoplasmic reticulumOne of 2 routes

fatty acidReach from here →

Catalysed by CEL, LIPAlysosome, cytosolOne of 4 routes

cholesteryl hexadecanoateReach from here →

Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 5 routes

cholesteryl (9Z,12Z)-octadecadienoateReach from here →

Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 5 routes

25-hydroxycholesterolReach from here →

Catalysed by CEL, LIPA, CH25Hlysosome, endoplasmic reticulum

cholesteryl (9Z-octadecenoate)Reach from here →

Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 5 routes

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →

Catalysed by CEL, LIPA, SLC27A2, ACSL4 and 6 morelysosome, cytosolOne of 3 routes

(25R)-cholest-5-ene-3beta,26-diolReach from here →

Catalysed by CEL, LIPA, CYP27A1lysosome, mitochondrial matrix

(17R,18S)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by CEL, LIPA, CYP1A1, CYP1A2 and 5 morelysosome

(17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by CEL, LIPA, CYP2C8, CYP2D6 and 1 morelysosome

19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, CYP2E1lysosome, endoplasmic reticulumOne of 3 routes

20-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, CYP4F2, CYP4F3 and 1 morelysosome

(5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoateReach from here →

Catalysed by CEL, LIPA, ALOX12Blysosome

cholesteryl octadecanoateReach from here →

Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 5 routes

cholesteryl (8Z,11Z,14Z)-eicosatrienoateReach from here →

Catalysed by CEL, LIPA, SOAT2, SOAT1lysosome, endoplasmic reticulumOne of 5 routes

(12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, ALOX12lysosome

(18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS1, PTGS2lysosome, cytosolOne of 2 routes

(15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

(11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

Catalysed by CEL, LIPA, CYP11A1, CYP1B1

lysosome, mitochondrial matrix

(5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS2, ALOX5lysosome

(5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by CEL, LIPA, PTGS1, PTGS2 and 1 morelysosome, cytosol

pregnenolone sulfateReach from here →

Catalysed by CEL, LIPA, CYP11A1, SULT2B1lysosome, mitochondrial matrix, cytosolOne of 4 routes

prostaglandin H3Reach from here →

Catalysed by CEL, LIPA, PTGS2lysosome

(24S)-hydroxycholesterol 24-sulfateReach from here →

Catalysed by CEL, LIPA, CYP46A1, SULT2A1lysosome, endoplasmic reticulum

(24S)-hydroxycholesterol 3-sulfateReach from here →

Catalysed by CEL, LIPA, CYP46A1, SULT2B1 and 2 morelysosome, endoplasmic reticulum

a 3-(acyloxy)acyl derivative of bacterial toxinReach from here →

Catalysed by CES1, LIPN, NCEH1, LDAH and 1 moreendoplasmic reticulum

(11Z,14Z,17Z-eicosatrienoyl)-cholesterolReach from here →

Catalysed by CES1, LIPN, NCEH1, LDAH and 1 moreendoplasmic reticulum