N(6)-(1,2-dicarboxyethyl)-AMP

1. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)

Catalysed by ADSL, TNRC6BcytosolOne of 2 routes

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)

Catalysed by ADSS2, ADSS1

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)

Catalysed by ADSS2, ADSS1

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
2. acetyl-CoA:L-aspartate N-acetyltransferase

Catalysed by ADSS2, ADSS1, NAT8Lmitochondrial matrix

1. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
2. a quinone + succinate = fumarate + a quinol

Catalysed by ADSL, TNRC6B, SDHBcytosol

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
2. L-tryptophan(out) + L-aspartate(in) = L-tryptophan(in) + L-aspartate(out)
3. beta-carboline hydrolysis

Catalysed by ADSS2, ADSS1, SLC7A13inner side of the membrane, outer side of the membrane, cytosol

1. IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)
2. acetyl-CoA:L-aspartate N-acetyltransferase
3. Carnitine O-Palmitoyltransferase

Catalysed by and 2 more