What it touches on the way
Mechanistic reach
18 entities
18 entities reached.
0 reported hops18 assembled from the scaffold
- SDHAProteinUNIPROT:P31040substrate ofInferred only27 paths27 endpoints
- DHODHProteinUNIPROT:Q02127substrate ofInferred only22 paths11 endpoints
- SDHBProteinUNIPROT:P21912substrate ofInferred only21 paths21 endpoints
- UQCRFS1ProteinUNIPROT:P47985substrate ofInferred only13 paths13 endpoints
- CYC1ProteinUNIPROT:P08574substrate ofInferred only12 paths12 endpoints
- GPD2ProteinUNIPROT:P43304substrate ofInferred only12 paths12 endpoints
- ETFAProteinUNIPROT:P13804substrate ofInferred only9 paths9 endpoints
- CHDHProteinUNIPROT:Q8NE62substrate ofInferred only9 paths9 endpoints
- SQORProteinUNIPROT:Q9Y6N5substrate ofInferred only7 paths7 endpoints
- UQCRC1ProteinUNIPROT:P31930substrate ofInferred only6 paths6 endpoints
- PRODHProteinUNIPROT:O43272substrate ofInferred only5 paths5 endpoints
- UQCRC2ProteinUNIPROT:P22695substrate ofInferred only5 paths5 endpoints
Show the remaining 6
- PRODH2ProteinUNIPROT:Q9UF12substrate ofInferred only5 paths5 endpoints
- UQCRQProteinUNIPROT:O14949substrate ofInferred only2 paths2 endpoints
- ETFBProteinUNIPROT:P38117substrate ofInferred only2 paths2 endpoints
- MT-CYBProteinUNIPROT:P00156substrate ofInferred only1 path1 endpoint
- ETFDHProteinUNIPROT:Q16134substrate ofInferred only1 path1 endpoint
- SDHCProteinUNIPROT:Q99643substrate ofInferred only1 path1 endpoint
What the reference databases state
Statements
32 statements
32 statements · 1 reference database · Subject: ubiquinol · Sources: Human-GEM
- 3-demethylubiquinol-10 is converted to ubiquinolCompoundHuman-GEM MAR06910Inferred only
- ubiquinones is converted to ubiquinolCompoundHuman-GEM MAR01808Inferred only
- ubiquinones is converted to ubiquinolCompoundHuman-GEM MAR06911Inferred only
- ubiquinones is converted to ubiquinolCompoundHuman-GEM MAR06921Inferred only
- ubiquinones is converted to ubiquinolCompoundHuman-GEM MAR20167Inferred only
- ubiquinol is converted to ubiquinonesCompoundHuman-GEM MAR20167Inferred only
- ubiquinol is converted to ubiquinonesCompoundHuman-GEM MAR06911Inferred only
- ubiquinones is converted to ubiquinolCompoundHuman-GEM MAR01801Inferred only
- ubiquinol is a substrate of CHDHProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of CYC1ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of DHODHProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of DHODHProteinHuman-GEM MAR20167Inferred only
Show the remaining 20
- ubiquinol is a substrate of ETFAProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of ETFBProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of ETFDHProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of GPD2ProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of MT-CYBProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of PRODHProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of PRODH2ProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of SDHAProteinHuman-GEM MAR04652Inferred only
- ubiquinol is a substrate of SDHBProteinHuman-GEM MAR04652Inferred only
- ubiquinol is a substrate of SDHCProteinHuman-GEM MAR04652Inferred only
- ubiquinol is a substrate of SDHDProteinHuman-GEM MAR04652Inferred only
- ubiquinol is a substrate of SQORProteinHuman-GEM MAR06911Inferred only
- ubiquinol is a substrate of UQCR10ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCR11ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRBProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRC1ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRC2ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRFS1ProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRHProteinHuman-GEM MAR06918Inferred only
- ubiquinol is a substrate of UQCRQProteinHuman-GEM MAR06918Inferred only
Reactions
17 reactions
MAM00209m+biotin+CHEBI:1146900+MAM01600m+ferroheme c di-L-cysteine(2-) residue+FADH2+(S)-carnitine+NADH(2-)+NADPH(4-)+riboflavin+5,6,7,8-tetrahydrobiopterin+5,6,7,8-tetrahydrofolic acid+ubiquinol+0.1MAM03139c+0.1MAM03140c+0.1MAM03143cMAM01602c
Reaction pageLeft to rightBalance undeterminableGO:0005759, GO:0005829
Human-GEM MAR00022CC BY 4.0Reference data
proton+NADPH(4-)+ubiquinonesNADP(3-)+ubiquinol
Reaction pageLeft to rightBalancedEC 1.8.1.9GO:0005829
Human-GEM MAR01801CC BY 4.0Reference data
proton+NADH(2-)+ubiquinonesNAD(+)+ubiquinol
Catalysed by NQO1
Reaction pageLeft to rightBalancedEC 1.8.1.9GO:0005829
Human-GEM MAR01808CC BY 4.0Reference data
fumaric acid+ubiquinolsuccinate(2-)+ubiquinones
Catalysed by SDHD & SDHB & SDHA & SDHC
Reaction pageReversibleBalancedEC 1.3.5.1GO:0005759
Human-GEM MAR04652CC BY 4.0Reference data
3-demethylubiquinol-10+S-adenosyl-L-methionineproton+CHEBI:16680+ubiquinol
Catalysed by COQ3
Reaction pageLeft to rightBalancedEC 2.1.1.64GO:0005759
Human-GEM MAR06910CC BY 4.0Reference data
FADH2+ubiquinonesFAD+ubiquinol
Catalysed by CHDH or PRODH or DHODH or ETFB or GPD2 or SQOR or ETFA or ETFDH or PRODH2
Reaction pageReversibleBalancedEC 1.5.5.1GO:0005759
Human-GEM MAR06911CC BY 4.0Reference data
2ferricytochrome c+2proton+ubiquinol2ferrocytochrome c+4proton+ubiquinones
Transported by UQCRQ & UQCR11 & MT-CYB & UQCRH & CYC1 & UQCRB & UQCRC2 & UQCRC1 & UQCRFS1 & UQCR10
Reaction pageLeft to rightBalancedEC 7.1.1.8GO:0005759, GO:0005758
Human-GEM MAR06918CC BY 4.0Reference data
5proton+NADH(2-)+ubiquinones4proton+NAD(+)+ubiquinol
Transported by NDUFS8 & COXFA4 & NDUFAB1 & NDUFA1 & NDUFS4 & NDUFB5 & NDUFB3 & NDUFC1 & NDUFA2 & NDUFS5 & NDUFS7 & NDUFS2 & NDUFS6 & NDUFB1 & NDUFS3 & NDUFB6 & NDUFA3 & NDUFB4 & NDUFB8 & NDUFB2 & NDUFA7 & NDUFC2 & NDUFA10 & NDUFB10 & MT-ND1 & MT-ND2 & MT-ND3 & MT-ND4L & MT-ND4 & MT-ND5 & MT-ND6 & NDUFB7 & NDUFV2 & NDUFS1 & NDUFV1 & NDUFA8 & NDUFV3 & NDUFA6 & NDUFA5 & NDUFA9 & NDUFA11 & NDUFB11 & NDUFA13 & NDUFA12 & NDUFB9
Reaction pageLeft to rightBalancedEC 7.1.1.2GO:0005759, GO:0005758
Human-GEM MAR06921CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR08967CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR08991CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005759, GO:0005829
Human-GEM MAR08997CC BY 4.0Reference data
0.034511-cis-retinol+0.0172all-trans-18-hydroxyretinoate+0.0172all-trans-18-hydroxyretinoate+0.0172MAM00611c+0.0172MAM00611m+0.0172MAM00622c+0.0172MAM00622m+0.0345MAM00766c+0.0172MAM01008c+0.0172MAM01008r+0.0172MAM01022c+0.0172MAM01022r+0.0172MAM01024c+0.0172MAM01024r+0.0345MAM01026r+0.0172MAM01028c+0.0172MAM01028r+0.0172MAM01030c+0.0172MAM01030r+0.0172all-trans-4-oxoretinoate+0.0172all-trans-4-oxoretinoate+0.0345all-trans-4-oxoretinol+0.0345MAM01060c+0.03459-cis-retinol+0.0345biotin+0.0345MAM01600m+0.0345FADH2+0.0345MAM01924c+0.0345heme b+0.0345(S)-carnitine+0.0345(R)-lipoate+0.0345MAM02624c+0.0345CHEBI:18405+0.0345riboflavin+0.03455,6,7,8-tetrahydrobiopterin+0.03455,6,7,8-tetrahydrofolic acid+0.0345thiamine(1+) diphosphate+0.0345ubiquinolMAM10012c
Reaction pageLeft to rightBalance undeterminableGO:0005829, GO:0005783, GO:0005759
Human-GEM MAR10065CC BY 4.0Reference data
Other names
6 names
Resolves to: ubiquinol
- Also called
- coenzymes QH2CoQH2QH(2)QH2reduced ubiquinoneubiquinols