Compound

N(6)-(1,2-dicarboxyethyl)-AMP

Tetraanion of N6-(1,2-dicarboxyethyl)-AMP arising from deprotonation of carboxylic acid and phosphate functions.

Definition from ChEBI (CHEBI:57567), read 2026-09-23. CC BY 4.0.

CHEBI:57567ChEBI

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Structure

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A generated conformer of N(6)-(1,2-dicarboxyethyl)-AMP — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C14H14N5O11P
Mass: 459.264 g/mol
Charge: -4
InChIKey: OFBHPPMPBOJXRT-DPXQIYNJSA-J
SMILES: O=C([O-])CC(Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])[O-])[C@@H](O)[C@H]1O)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

9 statements

9 statements · 2 reference databases · Subject: N(6)-(1,2-dicarboxyethyl)-AMP · Sources: Human-GEM, Rhea

Order

N(6)-(1,2-dicarboxyethyl)-AMP is converted to fumaric acidCompoundHuman-GEM MAR04412Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is converted to fumaric acidCompoundRhea RHEA:16853Inferred only
fumaric acid is converted to N(6)-(1,2-dicarboxyethyl)-AMPCompoundHuman-GEM MAR04412Inferred only
fumaric acid is converted to N(6)-(1,2-dicarboxyethyl)-AMPCompoundRhea RHEA:16853Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is a substrate of ADSLProteinHuman-GEM MAR04412Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is a substrate of ADSLProteinRhea RHEA:16853Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is a substrate of ADSS1ProteinRhea RHEA:15753Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is a substrate of ADSS2ProteinRhea RHEA:15753Inferred only
N(6)-(1,2-dicarboxyethyl)-AMP is a substrate of TNRC6BProteinHuman-GEM MAR04412Inferred only

Reactions

4 reactions

L-aspartate+GTP+CHEBI:17202N(6)-(1,2-dicarboxyethyl)-AMP+GDP+2proton+phosphate(3-)
Catalysed by ADSS2 or ADSS1
Reaction pageLeft to rightBalancedEC 6.3.4.4cytosol
Human-GEM MAR04042CC BY 4.0Reference data
AMP+fumaric acidN(6)-(1,2-dicarboxyethyl)-AMP
Catalysed by TNRC6B or ADSL
Reaction pageReversibleBalancedEC 4.3.2.2cytosol
Human-GEM MAR04412CC BY 4.0Reference data
IMP+L-aspartate+GTPN(6)-(1,2-dicarboxyethyl)-AMP+GDP+hydrogenphosphate+2hydron
Catalysed by ADSS2 or ADSS1
Reaction pageDirection not assertedBalanced
Rhea RHEA:15753CC BY 4.0Reference data
N(6)-(1,2-dicarboxyethyl)-AMPfumaric acid+AMP
Catalysed by ADSL
Reaction pageDirection not assertedBalanced
Rhea RHEA:16853CC BY 4.0Reference data

Other names

3 names

Resolves to: N(6)-(1,2-dicarboxyethyl)-AMP

Also called: N(6)-(1,2-dicarboxylatoethyl)-AMP tetraanionN6-(1,2-dicarboxylatoethyl)-AMP tetraanion
Systematic name: N-(1,2-dicarboxylatoethyl)-5'-O-phosphonatoadenosine