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Proteins/UNIPROT:Q16831
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds (Probable)..
Function from UniProtKB (Q16831), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
34 statements
34 statements · 5 reference databases · Subject: UPP1 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
4 reactions
phosphate(3-)+uridineD-ribose 1-phosphate+uracil
Reaction pageReversibleBalancedEC 2.4.2.3cytosol
Human-GEM MAR04579CC BY 4.0Reference data
MAM00639c+uracil2'-deoxyuridine+phosphate(3-)
Reaction pageReversible
3 names
Resolves to: UPP1
Human-GEM MAR04680CC BY 4.0Reference data
2'-deoxyuridine+hydrogenphosphate2-deoxy-alpha-D-ribose 1-phosphate+uracil
Reaction pageLeft to rightBalanced
Rhea RHEA:22824CC BY 4.0Reference data
uridine+hydrogenphosphatealpha-D-ribose 1-phosphate+uracil
Reaction pageLeft to rightBalanced
Rhea RHEA:24388CC BY 4.0Reference data