Compound
inosine
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C10H12N4O5
- Mass
- 268.229 g/mol
- Charge
- 0
- InChIKey
- UGQMRVRMYYASKQ-KQYNXXCUSA-N
- SMILES
- OC[C@H]1O[C@@H](n2cnc3c(O)ncnc32)[C@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Chemical structure
- 2'-deoxyinosine has the functional parent inosineCompoundChEBI CHEBI:28997Inferred only
- inosine has the functional parent hypoxanthineCompoundChEBI CHEBI:17596Inferred only
Statements
31 statements
31 statements · 2 reference databases · Subject: inosine · Sources: Human-GEM, Rhea
- adenosine is converted to inosineCompoundHuman-GEM MAR04481Inferred only
- adenosine is converted to inosineCompoundHuman-GEM MAR04482Inferred only
- adenosine is converted to inosineCompoundRhea RHEA:24408Inferred only
- inosine is converted to CHEBI:17202CompoundHuman-GEM MAR08484Inferred only
- CHEBI:17202 is converted to inosineCompoundHuman-GEM MAR04417Inferred only
- inosine is converted to CHEBI:17202CompoundHuman-GEM MAR08975Inferred only
- IMP is converted to inosineCompoundRhea RHEA:27718Inferred only
- inosine is converted to IMPCompoundRhea RHEA:21140Inferred only
- IMP is converted to inosineCompoundRhea RHEA:21140Inferred only
- inosine is a substrate of LACC1ProteinRhea RHEA:27646Inferred only
- inosine is a substrate of NT5C2ProteinRhea RHEA:69592Inferred only
- inosine is a substrate of NT5C2ProteinRhea RHEA:69596Inferred only
Show the remaining 19
- inosine is a substrate of NT5C2ProteinRhea RHEA:69572Inferred only
- inosine is a substrate of NT5C2ProteinRhea RHEA:69580Inferred only
- inosine is a substrate of NT5C2ProteinRhea RHEA:69584Inferred only
- inosine is a substrate of NT5C2ProteinRhea RHEA:69588Inferred only
- inosine is a substrate of PNPProteinRhea RHEA:27646Inferred only
- inosine is a substrate of PNPProteinHuman-GEM MAR04574Inferred only
- inosine is transported by SLC28A2ProteinHuman-GEM MAR06353Inferred only
- inosine is transported by SLC28A2ProteinRhea RHEA:69931Inferred only
- inosine is transported by SLC28A3ProteinRhea RHEA:69919Inferred only
- inosine is transported by SLC28A3ProteinHuman-GEM MAR06353Inferred only
- inosine is transported by SLC28A3ProteinHuman-GEM MAR06357Inferred only
- inosine is transported by SLC28A3ProteinHuman-GEM MAR11415Inferred only
- inosine is transported by SLC29A1ProteinRhea RHEA:75375Inferred only
- inosine is transported by SLC29A1ProteinHuman-GEM MAR05042Inferred only
- inosine is transported by SLC29A1ProteinHuman-GEM MAR08910Inferred only
- inosine is transported by SLC29A2ProteinHuman-GEM MAR05042Inferred only
- inosine is transported by SLC29A2ProteinRhea RHEA:75375Inferred only
- inosine is transported by SLC29A3ProteinRhea RHEA:75375Inferred only
- inosine is transported by SLC29A3ProteinHuman-GEM MAR01466Inferred only
Reactions
34 reactions
Transported by SLC29A3
Reaction pageReversibleBalancedlysosome, cytosol
Human-GEM MAR01466CC BY 4.0Reference data
water+CHEBI:17202inosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C or NT5E or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04417CC BY 4.0Reference data
adenosine+waterinosine+ammonium
Reaction pageLeft to rightBalancedEC 3.5.4.4cytosol
Human-GEM MAR04481CC BY 4.0Reference data
adenosine+waterinosine+ammonium
Reaction pageLeft to rightBalancedEC 3.5.4.4extracellular space
Human-GEM MAR04482CC BY 4.0Reference data
inosine+phosphate(3-)hypoxanthine+D-ribose 1-phosphate
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1cytosol
Human-GEM MAR04574CC BY 4.0Reference data
adenosine+inosineadenosine+inosine
Reaction pageReversibleBalancedEC 2.3.1.85cytosol, extracellular space
Human-GEM MAR04844CC BY 4.0Reference data
Transported by SLC29A1 or SLC29A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05042CC BY 4.0Reference data
inosine+sodium(1+)inosine+sodium(1+)
Transported by SLC28A2 or SLC28A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06353CC BY 4.0Reference data
inosine+2sodium(1+)inosine+2sodium(1+)
Transported by SLC28A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06357CC BY 4.0Reference data
ATP+inosineADP+proton+CHEBI:17202
Reaction pageLeft to rightBalancedmitochondrial matrix
Human-GEM MAR08484CC BY 4.0Reference data
Transported by SLC29A1
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR08910CC BY 4.0Reference data
ATP+inosineADP+proton+CHEBI:17202
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR08975CC BY 4.0Reference data
On the label
Labelled products
60 products
Source: NIH DSLD · Ingredient: inosine · 60 products · Declared amount per serving: 5–1,000 mg (24 products)
24 labels state an amount36 do not
- AdvoCareO2 Gold500 mgper 2 Caplet(s)DSLD:265465
- AdvoCarePost-Workout Recovery Chocolate 100 mgper 2 Ounce(s)DSLD:296897
- AdvoCarePost-Workout Recovery Vanilla100 mgper 60 Gram(s)DSLD:296898
- Allergy Research GroupOxyNutrients Electron Transport Formula150 mgper 1 Capsule(s)DSLD:20398
- Anabolic ResearchD-Anabol 25amount not statedper 1 Capsule(s)DSLD:269040
- BPI Sports1.M.R Apple Pearamount not statedper 8 Gram(s)DSLD:79840
- BPI Sports1.M.R Blueberry Lemonadeamount not statedper 8 Gram(s)DSLD:79844
- BPI Sports1.M.R Fruit Punchamount not statedper 8 Gram(s)DSLD:79846
- BPI Sports1.M.R Peach Cobbleramount not statedper 8 Gram(s)DSLD:79852
- BPI Sports1.M.R Rainbow Iceamount not statedper 8 Gram(s)DSLD:79857
- Cardiovascular ResearchInosine 500 mg500 mgper 1 Capsule(s)DSLD:304398
- Chaotic LabzEqualizer Tangerine Tarantulaamount not statedper 8 Gram(s)DSLD:271700
Show the remaining 48
- Chaotic-LabzCreamean Watermelon Rushamount not statedper 11 Gram(s)DSLD:41143
- Chaotic-LabzEqualizer Cherry Bombamount not statedper 8.3155 Gram(s)DSLD:72359
- Chaotic-LabzEqualizer Sucker Punchamount not statedper 9.32 Gram(s)DSLD:42200
- Controlled LabsWhite Floodamount not statedper 6.1 Gram(s)DSLD:2637
- DChGHamount not statedper 2 Tablet(s)DSLD:245413
- DChGHamount not statedper 2 Tablet(s)DSLD:265839
- DChGHamount not statedper 2 Tablet(s)DSLD:267264
- Douglas LaboratoriesEnergy/Sports Formulaamount not statedper 3 Tablet(s)DSLD:244630
- Douglas LaboratoriesEnergy/Sports Packamount not statedper 1 Packet(s)DSLD:9680
- Douglas LaboratoriesMale X Booster100 mgper 4 Vegetarian Capsule(s)DSLD:261222
- Douglas LaboratoriesPro-Equalizer Protein Powderamount not statedper 30 Gram(s)DSLD:8602
- Douglas LaboratoriesPro-Equalizer Protein Powderamount not statedper 30 Gram(s)DSLD:8599
- Ecological FormulasFree Radical Quenchers5 mgper 1 Capsule(s)DSLD:299771
- Ecological FormulasIGA+Intercellular Glutathione Inducers5 mgper 1 Capsule(s)DSLD:22684
- Ecological FormulasMonolaurin 300 mg7.5 mgper 1 Capsule(s)DSLD:22885
- Ecological FormulasMonolaurin 600 mg7.5 mgper 1 Capsule(s)DSLD:22890
- Foster RegalhGH Supportamount not statedper 2 Tablet(s)DSLD:296998
- Gaspari NutritionPlasmaJetamount not statedper 2 Capsule(s)DSLD:292003
- Healthy Choice NaturalsVirility-XL50 mgper 2 Capsule(s)DSLD:72185
- Hi-Tech PharmaceuticalsAnavaramount not statedper 3 Tablet(s)DSLD:242302
- InfoWars M.DLibido RX50 mgper 2 Capsule(s)DSLD:307120
- MMUSAResprimax Natural Elderberryamount not statedper 1 mLDSLD:327369
- Moss NutritionLauric Select7.5 mgper 1 Capsule(s)DSLD:275529
- MuscleTechAlpha Amino Prototype 216amount not statedper 6 Caplet(s)DSLD:4212
- MuscleTechAnabolic Halo Hardcore Pro Series Arctic Fruit Punchamount not statedper 23 Gram(s)DSLD:4963
- MuscleTechAnabolic Halo Hardcore Pro Series Blue Raspberry Glacieramount not statedper 23 Gram(s)DSLD:4964
- MuscleTechAnabolic Halo Hardcore Pro Series Orange Avalancheamount not statedper 23 Gram(s)DSLD:4245
- MuscleTechCell-Tech Hardcore Pro Series Blue Raspberryamount not statedper 100 Gram(s)DSLD:6514
- MuscleTechCell-Tech Hardcore Pro Series Grapeamount not statedper 100 Gram(s)DSLD:6516
- MuscleTechCell-Tech Hardcore Pro Series Lemon Limeamount not statedper 100 Gram(s)DSLD:6517
- MuscleTechCell-Tech Hardcore Pro Series Orangeamount not statedper 100 Gram(s)DSLD:6518
- MuscleTechCell-Tech Haredcore Pro Series Fruit Punchamount not statedper 100 Gram(s)DSLD:6515
- MuscleTech Pro SeriesnaNO Vapor Hardcore Blue Raspberry Glacieramount not statedper 18 Gram(s)DSLD:6526
- MuscleTech Pro SeriesnaNO Vapor Hardcore Fruit Punchamount not statedper 18 Gram(s)DSLD:6525
- MuscleTech Pro SeriesnaNO Vapor Hardcore Orange Hazeamount not statedper 18 Gram(s)DSLD:6527
- Natures PlusUIltra Skinny MiniHXRamount not statedper 1 Tablet(s)DSLD:69299
- Source NaturalsTriathlete300 mgper 4 Tablet(s)DSLD:78034
- Source NaturalsTriathlete300 mgper 4 Tablet(s)DSLD:78047
- Source Naturals Athletic SeriesInosine 500 mg500 mgper 1 Tablet(s)DSLD:295893
- SwansonInosine500 mgper 1 Veggie Capsule(s)DSLD:308629
- Ultimate Nutrition Platinum SeriesInosineHypoxanthine Riboside1,000 mgper 2 Capsule(s)DSLD:293462
- UniversalPower Protein Chocolate Flavor25 mgper 30 Gram(s)DSLD:38310
- UniversalPower Protein Vanilla Flavor25 mgper 30 Gram(s)DSLD:38313
- UniversalUniversal Power Protein Chocolate Flavor25 mgper 30 Gram(s)DSLD:66417
- UniversalUniversal Power Protein Vanilla Flavor25 mgper 30 Gram(s)DSLD:66219
- VitolRussian Bear500 mgper 8 Tablet(s)DSLD:18005
- Wonder LaboratorieshGH Activatoramount not statedper 2 Tablet(s)DSLD:260458
- XtendlifeNatural Energy100 mgper 3 Capsule(s)DSLD:283389
Label record: NIH Office of Dietary Supplements · CC0
Where it reaches
6 systems, 14 regions, 41 tissues, 43 transporter routes — routes, not measurements: transporters known to carry inosine are expressed there, and no source reports it arriving.
Loading the model…
Other names
9 names
Resolves to: inosine
- Also called
- 9-beta-D-ribofuranosyl-9H-purin-6-ol9-beta-D-ribofuranosylhypoxanthine9-β-D-ribofuranosyl-9H-purin-6-ol9-β-D-ribofuranosylhypoxanthinehypoxanthine D-ribosidehypoxanthosine
- Systematic name
- (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-3,4-diol9-(beta-D-ribofuranosyl)-9H-purin-6-ol9-(β-D-ribofuranosyl)-9H-purin-6-ol