Compound
2'-deoxyguanosine
A nucleoside consisting of the base guanine and the sugar deoxyribose.
Structure
No depiction stored
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- Class
- Organic compound
- Formula
- C10H13N5O4
- Mass
- 267.245 g/mol
- Charge
- 0
- InChIKey
- YKBGVTZYEHREMT-KVQBGUIXSA-N
- SMILES
- Nc1nc(=O)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2n1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- SLC29A1ProteinUNIPROT:Q99808transported byInferred only86 paths43 endpoints
- PNPProteinUNIPROT:P00491substrate ofInferred only72 paths36 endpoints
- NT5C2ProteinUNIPROT:P49902substrate ofInferred only12 paths12 endpoints
- SAMHD1ProteinUNIPROT:Q9Y3Z3substrate ofInferred only9 paths9 endpoints
- SLC29A2ProteinUNIPROT:Q14542transported byInferred only6 paths3 endpoints
- DGUOKProteinUNIPROT:Q16854substrate ofInferred only6 paths3 endpoints
What the reference databases state
Chemical structure
- 2'-deoxyguanosine has the functional parent guanosineCompoundChEBI CHEBI:17172Inferred only
Statements
16 statements
16 statements · 2 reference databases · Subject: 2'-deoxyguanosine · Sources: Human-GEM, Rhea
- 2'-deoxyguanosine is converted to dGMPCompoundHuman-GEM MAR04601Inferred only
- 2'-deoxyguanosine is converted to dGMPCompoundHuman-GEM MAR04600Inferred only
- dGMP is converted to 2'-deoxyguanosineCompoundHuman-GEM MAR04602Inferred only
- dGMP is converted to 2'-deoxyguanosineCompoundHuman-GEM MAR08495Inferred only
- 2'-deoxyguanosine is a substrate of DGUOKProteinHuman-GEM MAR04600Inferred only
- 2'-deoxyguanosine is a substrate of DGUOKProteinHuman-GEM MAR04601Inferred only
- 2'-deoxyguanosine is a substrate of NT5C2ProteinRhea RHEA:69580Inferred only
- 2'-deoxyguanosine is a substrate of PNPProteinHuman-GEM MAR04603Inferred only
- 2'-deoxyguanosine is a substrate of PNPProteinRhea RHEA:27738Inferred only
- 2'-deoxyguanosine is a substrate of SAMHD1ProteinRhea RHEA:15193Inferred only
- 2'-deoxyguanosine is transported by SLC28A2ProteinHuman-GEM MAR05041Inferred only
- 2'-deoxyguanosine is transported by SLC28A3ProteinHuman-GEM MAR06359Inferred only
Show the remaining 4
- 2'-deoxyguanosine is transported by SLC29A1ProteinHuman-GEM MAR04997Inferred only
- 2'-deoxyguanosine is transported by SLC29A1ProteinHuman-GEM MAR06366Inferred only
- 2'-deoxyguanosine is transported by SLC29A2ProteinHuman-GEM MAR06366Inferred only
- 2'-deoxyguanosine is transported by SLC29A2ProteinHuman-GEM MAR04997Inferred only
Reactions
18 reactions
ATP+2'-deoxyguanosineADP+dGMP+proton
Catalysed by DGUOK
Reaction pageLeft to rightBalancedEC 2.7.1.113GO:0005829
Human-GEM MAR04600CC BY 4.0Reference data
ATP+2'-deoxyguanosineADP+dGMP+proton
Catalysed by DGUOK
Reaction pageLeft to rightBalancedEC 2.7.1.113GO:0005759
Human-GEM MAR04601CC BY 4.0Reference data
dGMP+water2'-deoxyguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5GO:0005829
Human-GEM MAR04602CC BY 4.0Reference data
MAM00639c+guanine2'-deoxyguanosine+phosphate(3-)
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1, 2.4.2.4GO:0005829
Human-GEM MAR04603CC BY 4.0Reference data
2'-deoxyguanosine2'-deoxyguanosine
Transported by SLC29A1 or SLC29A2
Reaction pageLeft to rightBalancedGO:0005829, GO:0005759
Human-GEM MAR04997CC BY 4.0Reference data
2'-deoxyguanosine+sodium(1+)2'-deoxyguanosine+sodium(1+)
Transported by SLC28A2
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR05041CC BY 4.0Reference data
2'-deoxyguanosine+2sodium(1+)2'-deoxyguanosine+2sodium(1+)
Transported by SLC28A3
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR06359CC BY 4.0Reference data
2'-deoxyguanosine2'-deoxyguanosine
Transported by SLC29A1 or SLC29A2
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR06366CC BY 4.0Reference data
dGMP+water2'-deoxyguanosine+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2GO:0005764
Human-GEM MAR08495CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09300CC BY 4.0Reference data
dGTP+water2'-deoxyguanosine+triphosphate+hydron
Catalysed by SAMHD1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15193CC BY 4.0Reference data
2'-deoxyguanosine+ATP(4-)dGMP+ADP(3-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:19201CC BY 4.0Reference data
Where it reaches
6 systems, 14 regions, 41 tissues, 43 transporter routes — routes, not measurements: transporters known to carry 2'-deoxyguanosine are expressed there, and no source reports it arriving.
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Other names
7 names
Resolves to: 2'-deoxyguanosine
- Also called
- 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-9H-purin-6-ol2-amino-9-(2-deoxy-9-β-D-ribofuranosyl)-9H-purin-6-ol9-(2-deoxy-beta-D-erythro-pentofuranosyl)-guanine9-(2-deoxy-β-D-erythro-pentofuranosyl)-guanineDeoxyguanosinedGguanine deoxy nucleoside