guanine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

37 compounds within 3 steps: 4 in 1, 9 in 2, 24 in 3

One step

guanosineReach from here →
1. guanosine:phosphate alpha-D-ribosyltransferase
Catalysed by PNPcytosol
2'-deoxyguanosineReach from here →
1. Deoxyguanosine:orthophosphate ribosyltransferase
Catalysed by PNPcytosolOne of 2 routes
queuineReach from here →
1. tRNA-guanosine34:queuine tRNA-D-ribosyltransferase
Catalysed by QTRT1, QTRT2cytosolOne of 2 routes
xanthineReach from here →
1. Guanine aminohydrolase
Catalysed by GDAcytosolOne of 2 routes

Two steps

hypoxanthineReach from here →
1. Guanine aminohydrolase
2. hypoxanthine + NAD(+) + H2O = xanthine + NADH + H(+)
Catalysed by GDA, XDHcytosol
inosineReach from here →
1. Deoxyguanosine:orthophosphate ribosyltransferase
2. dGMP + inosine = 2'-deoxyguanosine + IMP
Catalysed by PNP, NT5C2cytosolOne of 2 routes
urateReach from here →

Three steps

beta-nicotinamide D-ribosideReach from here →
Catalysed by PNPcytosol
CHEBI:16174Reach from here →
Catalysed by PNP, DGUOKcytosol, mitochondrial matrix

Guanine aminohydrolase

xanthine:NAD+ oxidoreductase

Catalysed by GDA, XDHcytosolOne of 6 routes

xanthosineReach from here →

Catalysed by GDA, PNPcytosolOne of 2 routes

D-ribose 1-phosphateReach from here →

Catalysed by PNPcytosol

2-deoxy-alpha-D-ribose 1-phosphateReach from here →

Catalysed by PNPcytosol

XMPReach from here →

Catalysed by GDA, HPRT1cytosol

dGMPReach from here →

Catalysed by PNP, DGUOKcytosolOne of 4 routes

alpha-D-ribose 1-phosphateReach from here →

Catalysed by PNP, LACC1cytosol

urea

Reach from here →

Catalysed by GDA, XDH, MPOcytosol, nucleusOne of 3 routes

adenosineReach from here →

Catalysed by PNP, NT5C2cytosol, extracellular spaceOne of 4 routes

(S)-lactateReach from here →

Catalysed by GDA, XDH, SLC22A12, SLC22A13cytosol, inner side of the membrane, outer side of the membrane

uridineReach from here →

Catalysed by PNP, NT5C2cytosolOne of 2 routes

CHEBI:17202Reach from here →

Catalysed by GDA, XDH, HPRT1cytosolOne of 3 routes

CHEBI:17208Reach from here →

Catalysed by GDA, XDHcytosol

cytidineReach from here →

Catalysed by PNP, NT5C2cytosol

CHEBI:17797Reach from here →

Catalysed by PNP, PGM2cytosol

5-hydroxyisourateReach from here →

Catalysed by GDA, XDHcytosol

CHEBI:28862Reach from here →

Catalysed by PNP, DGUOK, GUK1cytosolOne of 2 routes

a dicarboxylateReach from here →

Catalysed by GDA, XDH, SLC22A6cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

2'-deoxyinosineReach from here →

Catalysed by GDA, XDH, PNPcytosolOne of 4 routes

glutarateReach from here →

Catalysed by GDA, XDH, SLC22A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

nicotinateReach from here →

Catalysed by GDA, XDH, SLC22A12, SLC22A13cytosol, inner side of the membrane, outer side of the membrane

(S)-lactic acidReach from here →

Catalysed by GDA, XDH, SLC22A12cytosol, extracellular space

glutathioneReach from here →

Catalysed by GDA, XDH, SLC22A13cytosol, inner side of the membrane, outer side of the membrane

IMPReach from here →

Catalysed by GDA, HPRT1, IMPDH2, IMPDH1cytosolOne of 9 routes

(2R)-3-phosphoglycerateReach from here →

Catalysed by PNP, PGM2L1cytosolOne of 2 routes

2-deoxy-D-ribose 5-phosphateReach from here →

Catalysed by PNP, PGM2cytosol

alpha-D-ribose 1,5-bisphosphateReach from here →

Catalysed by PNP, LACC1, PGM2L1cytosol

CHEBI:730073Reach from here →

Catalysed by GDA, XDH, MPOcytosol, nucleusOne of 3 routes

D-ribose 5-phosphateReach from here →

Catalysed by PNP, LACC1, PGM2cytosol