Compound
dUMP
A 2'-deoxyribonucleoside 5'-monophosphate(2−) obtained by deprotonation of the phosphate OH groups of 2'-deoxyuridine 5'-monophosphate (dUMP); major species at pH 7.3.
Definition from ChEBI (CHEBI:246422), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
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- Class
- Organic compound, anion
- Formula
- C9H11N2O8P
- Mass
- 306.167 g/mol
- Charge
- -2
- InChIKey
- JSRLJPSBLDHEIO-SHYZEUOFSA-L
- SMILES
- O=c1ccn([C@H]2C[C@H](O)[C@@H](COP(=O)([O-])[O-])O2)c(=O)n1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- SLC25A36ProteinUNIPROT:Q96CQ1transported byInferred only78 paths39 endpoints
- TYMSProteinUNIPROT:P04818substrate ofInferred only48 paths24 endpoints
- NT5CProteinUNIPROT:Q8TCD5substrate ofInferred only24 paths8 endpoints
- NT5MProteinUNIPROT:Q9NPB1substrate ofInferred only12 paths4 endpoints
- DUTProteinUNIPROT:P33316substrate ofInferred only11 paths11 endpoints
What the reference databases state
Statements
29 statements
29 statements · 2 reference databases · Subject: dUMP · Sources: Human-GEM, Rhea
- dUMP is converted to 2'-deoxyuridineCompoundRhea RHEA:29355Inferred only
- dUMP is converted to 2'-deoxyuridineCompoundHuman-GEM MAR04642Inferred only
- dUMP is converted to 2'-deoxyuridineCompoundHuman-GEM MAR06626Inferred only
- 2'-deoxyuridine is converted to dUMPCompoundHuman-GEM MAR04641Inferred only
- 2'-deoxyuridine is converted to dUMPCompoundHuman-GEM MAR06625Inferred only
- 2'-deoxyuridine is converted to dUMPCompoundRhea RHEA:28206Inferred only
- 2'-deoxyuridine is converted to dUMPCompoundRhea RHEA:29355Inferred only
- dCMP is converted to dUMPCompoundRhea RHEA:22924Inferred only
- dCMP is converted to dUMPCompoundHuman-GEM MAR04507Inferred only
- dUMP is converted to dCTPCompoundRhea RHEA:19205Inferred only
- dCTP is converted to dUMPCompoundRhea RHEA:19205Inferred only
- dUTP is converted to dUMPCompoundHuman-GEM MAR11398Inferred only
Show the remaining 17
- dUTP is converted to dUMPCompoundRhea RHEA:10248Inferred only
- dUMP is converted to dUTPCompoundRhea RHEA:64964Inferred only
- dUMP is converted to dUTPCompoundRhea RHEA:10248Inferred only
- dUTP is converted to dUMPCompoundRhea RHEA:64964Inferred only
- dUTP is converted to dUMPCompoundHuman-GEM MAR04643Inferred only
- dUTP is converted to dUMPCompoundHuman-GEM MAR08483Inferred only
- dUMP is a substrate of DUTProteinRhea RHEA:10248Inferred only
- dUMP is a substrate of NT5CProteinRhea RHEA:29355Inferred only
- dUMP is a substrate of NT5CProteinHuman-GEM MAR06626Inferred only
- dUMP is a substrate of NT5CProteinHuman-GEM MAR04642Inferred only
- dUMP is a substrate of NT5MProteinHuman-GEM MAR06626Inferred only
- dUMP is a substrate of NT5MProteinRhea RHEA:29355Inferred only
- dUMP is a substrate of NT5MProteinHuman-GEM MAR04642Inferred only
- dUMP is a substrate of TYMSProteinHuman-GEM MAR04644Inferred only
- dUMP is a substrate of TYMSProteinRhea RHEA:12104Inferred only
- dUMP is transported by SLC25A36ProteinHuman-GEM MAR20151Inferred only
- dUMP is transported by SLC25A36ProteinRhea RHEA:73595Inferred only
Reactions
30 reactions
MAM01754c+waterdUMP+proton+phosphate(3-)
Catalysed by DUT
Reaction pageLeft to rightBalancedEC 3.6.1.23cytosol
Human-GEM MAR03965CC BY 4.0Reference data
Reaction pageReversibleBalancedEC 2.7.4.9cytosol
Human-GEM MAR03968CC BY 4.0Reference data
Catalysed by DCTD
Reaction pageLeft to rightBalancedEC 3.5.4.12cytosol
Human-GEM MAR04507CC BY 4.0Reference data
Reaction pageLeft to rightBalancedEC 2.7.4.4, 2.7.4.9mitochondrial matrix
Human-GEM MAR04640CC BY 4.0Reference data
ATP+2'-deoxyuridineADP+dUMP+proton
Catalysed by TK1
Reaction pageLeft to rightBalancedEC 2.7.1.21cytosol
Human-GEM MAR04641CC BY 4.0Reference data
dUMP+water2'-deoxyuridine+phosphate(3-)
Reaction pageLeft to rightBalancedEC 3.1.3.-cytosol
Human-GEM MAR04642CC BY 4.0Reference data
dUTP+waterdUMP+proton+diphosphate(3-)
Catalysed by DUT
Reaction pageLeft to rightBalancedEC 3.6.1.23, 3.6.1.9mitochondrial matrix
Human-GEM MAR04643CC BY 4.0Reference data
(6R)-5,10-methylenetetrahydrofolic acid+dUMP7,8-dihydrofolate+dTMP
Catalysed by TYMS
Reaction pageLeft to rightBalancedEC 2.1.1.45cytosol
Human-GEM MAR04644CC BY 4.0Reference data
Reaction pageLeft to rightBalancedmitochondrial matrix, cytosol
Human-GEM MAR04850CC BY 4.0Reference data
2'-deoxyuridine+CHEBI:16497CHEBI:28862+dUMP+proton
Reaction pageLeft to rightBalancedEC 2.7.1.21cytosol
Human-GEM MAR06623CC BY 4.0Reference data
2'-deoxyuridine+CHEBI:16497CHEBI:28862+dUMP+proton
Catalysed by TK2
Reaction pageLeft to rightBalancedEC 2.7.1.21mitochondrial matrix
Human-GEM MAR06624CC BY 4.0Reference data
ATP+2'-deoxyuridineADP+dUMP+proton
Catalysed by TK2
Reaction pageLeft to rightBalancedEC 2.7.1.21mitochondrial matrix
Human-GEM MAR06625CC BY 4.0Reference data
Where it reaches
7 systems, 13 regions, 39 tissues, 39 transporter routes — routes, not measurements: transporters known to carry dUMP are expressed there, and no source reports it arriving.
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Other names
6 names
Resolves to: dUMP
- Also called
- deoxyuridine 5'-phosphate dianiondeoxyuridine 5'-phosphate(2-)deoxyuridine 5'-phosphate(2−)deoxyuridylatedUMP dianion
- Systematic name
- 2'-deoxy-5'-O-phosphonatouridine