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Proteins/UNIPROT:Q9NPB1
Dephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates. Shows low activity toward dGMP and marginal activity toward dIMP..
Function from UniProtKB (Q9NPB1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
39 statements
39 statements · 6 reference databases · Subject: NT5M · Sources: Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
19 reactions
5 names
Resolves to: NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5, 3.1.3.35cytosol
Human-GEM MAR04056CC BY 4.0Reference data
AMP+wateradenosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04081CC BY 4.0Reference data
GMP+waterguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04450CC BY 4.0Reference data
dTMP+waterphosphate(3-)+thymidine
Catalysed by ACP3 or NT5C3A or NT5C or NT5E or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5, 3.1.3.35mitochondrial matrix
Human-GEM MAR04484CC BY 4.0Reference data
MAM01639c+water2'-deoxyadenosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04632CC BY 4.0Reference data
dUMP+water2'-deoxyuridine+phosphate(3-)
Reaction pageLeft to rightBalancedEC 3.1.3.-cytosol
Human-GEM MAR04642CC BY 4.0Reference data
water+MAM02735ca 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)+phosphate(3-)
Catalysed by MTMR7 or PHPT1 or MTMR1 or MTMR2 or MTMR8 or TNS2 or NT5DC3 or FIG4 or NT5C or CTDSPL2 or PTPRQ or MTMR6 and 8 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 3.1.3.-cytosol
Human-GEM MAR06591CC BY 4.0Reference data
dUMP+water2'-deoxyuridine+phosphate(3-)
Reaction pageLeft to rightBalancedEC 3.1.3.-mitochondrial matrix
Human-GEM MAR06626CC BY 4.0Reference data
water+UMPphosphate(3-)+uridine
Catalysed by NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5lysosome
Human-GEM MAR07716CC BY 4.0Reference data
water+UMPphosphate(3-)+uridine
Catalysed by NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5mitochondrial matrix
Human-GEM MAR07717CC BY 4.0Reference data
dTMP+waterphosphate(3-)+thymidine
Catalysed by NT5C1A or NT5C or NT5E or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.-lysosome
Human-GEM MAR07725CC BY 4.0Reference data