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Proteins/UNIPROT:P21589
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN..
Function from UniProtKB (P21589), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
220 statements
220 statements · 7 reference databases · Subject: NT5E · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
34 reactions
8 names
Resolves to: NT5E
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04010CC BY 4.0Reference data
dTMP+waterphosphate(3-)+thymidine
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5, 3.1.3.35cytosol
Human-GEM MAR04056CC BY 4.0Reference data
AMP+wateradenosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04081CC BY 4.0Reference data
AMP+wateradenosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5E or NT5C3B or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5mitochondrial matrix
Human-GEM MAR04082CC BY 4.0Reference data
cytidine 5'-monophosphate+watercytidine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04177CC BY 4.0Reference data
cytidine 5'-monophosphate+watercytidine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04179CC BY 4.0Reference data
water+nicotinic acid D-ribonucleotidebeta-D-ribosylnicotinate+phosphate(3-)
Catalysed by ACP3 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04252CC BY 4.0Reference data
water+NMN zwitterionbeta-nicotinamide D-riboside+phosphate(3-)
Catalysed by ACP3 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04264CC BY 4.0Reference data
water+CHEBI:17202inosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C or NT5E or RBAK or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04417CC BY 4.0Reference data
GMP+waterguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04449CC BY 4.0Reference data
GMP+waterguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04450CC BY 4.0Reference data