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Proteins/UNIPROT:Q16633
Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator (By similarity)..
Function from UniProtKB (Q16633), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
127 statements
127 statements · 3 reference databases · Subject: POU2AF1 · Sources: gene ontology, Hetionet, WikiPathways
6 names
Resolves to: POU2AF1