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Proteins/UNIPROT:Q9Y2D2
Transports diphosphate-N-acetylglucosamine (UDP-GlcNAc) from the cytosol into the lumen of the Golgi apparatus, functioning as an antiporter that exchanges UDP-N-acetyl-alpha-D-glucosamine for UMP. May supply UDP-GlcNAc as substrate for Golgi-resident glycosyltransferases that generate highly branched, multiantennary complex N-glycans and keratan sulfate. However, the exact role of SLC35A3 still needs to be elucidated, it could be a member of a catalytically more efficient multiprotein complex rather than function independently as a single transporter..
Function from UniProtKB (Q9Y2D2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
254 statements
254 statements · 4 reference databases · Subject: SLC35A3 · Sources: Bgee, Hetionet, Reactome, Rhea
1 reaction
UMP+UDP-N-acetyl-alpha-D-glucosamineUMP+UDP-N-acetyl-alpha-D-glucosamine
Transported by SLC35A2 or SLC35D4 or SLC35D2 or SLC35G3 or SLC35A5 or SLC35D1 or SLC35A3
Reaction pageDirection not assertedBalanced
Rhea RHEA:72695CC BY 4.0Reference data
2 names
Resolves to: SLC35A3