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Proteins/UNIPROT:O43447
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone..
Function from UniProtKB (O43447), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
186 statements
186 statements · 3 reference databases · Subject: PPIH · Sources: gene ontology, Hetionet, Reactome
2 reactions
7 names
Resolves to: PPIH
[protein]-peptidylproline (omega=180)[protein]-peptidylproline (omega=0)
Catalysed by PPIH or FKBP9 or PPIB or FKBP2 or PPIF or NKTR or PPIC or PPIA or FKBP1A or FKBP1B or FKBP3 or FKBP4 and 16 more alternatives
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16237CC BY 4.0Reference data