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Proteins/UNIPROT:Q9NXK8
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the polyubiquitination and proteasomal degradation of CAMK1 leading to disruption of cyclin D1/CDK4 complex assembly which results in G1 cell cycle arrest in lung epithelia..
Function from UniProtKB (Q9NXK8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
339 statements
339 statements · 3 reference databases · Subject: FBXL12 · Sources: gene ontology, Hetionet, Reactome · Rows fetched: 300
3 names
Resolves to: FBXL12