Pathway
Synthesis of UDP-N-acetyl-glucosamine
UDP-acetylglucosamine acts as a donor for the first two steps of the N-glycan precursor biosynthesis pathway, and is later used as a substrate for further modifications after the precursor has been attached to the protein. It is synthesized from fructose 6-phosphate, glutamine, acetyl-CoA, and UTP in four steps.
REACT:R-HSA-446210Reactome
What the reference databases state
Statements
8 statements
8 statements · 1 reference database · Subject: Synthesis of UDP-N-acetyl-glucosamine · Sources: Reactome
- AMDHD2 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- GFPT1 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- GFPT2 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- GNPNAT1 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- NAGK participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- PGM3 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- RENBP participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only
- UAP1 participates in Synthesis of UDP-N-acetyl-glucosamineProteinReactome R-HSA-446210Inferred only