Loading the page.
Proteins/UNIPROT:O95983
Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to methylated DNA by itself. Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases..
Function from UniProtKB (O95983), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
87 statements
87 statements · 4 reference databases · Subject: MBD3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
2 names
Resolves to: MBD3