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Proteins/UNIPROT:Q8NFW8
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
Function from UniProtKB (Q8NFW8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
101 statements
101 statements · 6 reference databases · Subject: CMAS · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea
4 reactions
CHEBI:17677+N-glycoloylneuraminateMAM01593c+diphosphate(3-)
Catalysed by CMAS
Reaction pageLeft to rightBalancedEC 2.7.7.43cytosol
Human-GEM MAR04532CC BY 4.0Reference data
CHEBI:17677+N-acetyl-beta-neuraminic acidCMP-N-acetyl-beta-neuraminate+diphosphate(3-)
Catalysed by CMAS
Reaction pageLeft to rightBalancedEC 2.7.7.43nucleus
2 names
Resolves to: CMAS
CHEBI:17677+N-acetyl-beta-neuraminic acidCMP-N-acetyl-beta-neuraminate+diphosphate(3-)
Catalysed by CMAS
Reaction pageLeft to rightBalancedEC 2.7.7.43cytosol
Human-GEM MAR08377CC BY 4.0Reference data
an N-acylneuraminate+CTPa CMP-N-acyl-beta-neuraminate+diphosphate(3-)
Catalysed by CMAS
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:11344CC BY 4.0Reference data