CMP-N-acetyl-beta-neuraminate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

200 compounds within 3 steps: 51 in 1, 18 in 2, 131 in 3

One step

an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivativeReach from here →
1. a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)
Catalysed by ST6GAL1, ST6GAL2
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivativeReach from here →
1. a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)
Catalysed by ST3GAL3, ST3GAL4, ST3GAL6
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivativeReach from here →
1. a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+)
Catalysed by ST3GAL4
an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
1. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL4, ST3GAL2
an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivativeReach from here →
1. an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->8)-N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl derivative + CMP + H(+)
Catalysed by ST8SIA3, ST8SIA1
a globoside MSGGReach from here →
1. a globoside GalGb4Cer + CMP-N-acetyl-beta-neuraminate = a globoside MSGG + CMP + H(+)
Catalysed by ST3GAL2
a globoside DSGGReach from here →
1. a globoside MSGG + CMP-N-acetyl-beta-neuraminate = a globoside DSGG + CMP + H(+)
Catalysed by ST6GALNAC3, ST6GALNAC6
a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivativeReach from here →
1. a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)
Catalysed by ST6GALNAC1, ST6GALNAC2
a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer(d18:1(4E))Reach from here →
1. a neolactoside nLc6Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a neolactoside VI(3)-alpha-NeuNAc-nLc6Cer(d18:1(4E)) + CMP + H(+)
Catalysed by ST3GAL6
an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivativeReach from here →
1. an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc derivative + CMP + H(+)
Catalysed by ST6GALNAC3, ST6GALNAC4
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamineReach from here →
1. N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine + CMP + H(+)
Catalysed by ST6GALNAC4
an alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivativeReach from here →
1. an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + CMP + H(+)
Catalysed by ST8SIA3
alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAcReach from here →
1. alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAc + CMP-N-acetyl-beta-neuraminate = alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-6S-D-GlcNAc + CMP + H(+)
Catalysed by ST8SIA3
CMP-N-acetyl-9-O-acetyl-beta-neuraminateReach from here →
1. CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-9-O-acetyl-beta-neuraminate + CoA
Catalysed by CASD1
CMP-N-acetyl-7-O-acetyl-beta-neuraminateReach from here →
1. CMP-N-acetyl-beta-neuraminate + acetyl-CoA = CMP-N-acetyl-7-O-acetyl-beta-neuraminate + CoA
Catalysed by CASD1
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))Reach from here →
1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST3GAL6cytosolOne of 3 routes
a ganglioside GM3 (d18:1(4E))Reach from here →
1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST3GAL5cytosolOne of 3 routes
a ganglioside GM2 (d18:1(4E))Reach from here →
1. lactosylceramide alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST6GALNAC2, ST3GAL5cytosol
ganglioside GM1 (d18:1(4E)/18:0)Reach from here →
1. ganglioside GA1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GM1 (d18:1(4E)/18:0) + CMP + H(+)
Catalysed by ST3GAL5
a ganglioside GM1 (d18:1(4E))Reach from here →
1. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST3GAL5cytosol
a ganglioside GD3 (d18:1(4E))Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA1cytosolOne of 4 routes
a ganglioside GT3 (d18:1(4E))Reach from here →
1. alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA5, ST8SIA1cytosolOne of 3 routes
a ganglioside GD1a (d18:1(4E))Reach from here →
1. ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST6GALNAC3, ST6GALNAC6, ST6GALNAC5, ST6GALNAC4cytosolOne of 4 routes
a ganglioside GT1a (d18:1(4E))Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA5cytosolOne of 3 routes
a ganglioside GT1b (d18:1(4E))Reach from here →
1. beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST3GAL1, ST3GAL4, ST3GAL2cytosolOne of 4 routes
a ganglioside GQ1b (d18:1(4E))Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA5cytosolOne of 4 routes
a ganglioside GM4 (d18:1(4E))Reach from here →
1. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
Catalysed by ST3GAL5
ganglioside GM2 (d18:1(4E)/18:0)Reach from here →
1. ganglioside GA2 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GM2 (d18:1(4E)/18:0) + CMP + H(+)
Catalysed by ST3GAL5
a ganglioside GD2 (d18:1(4E))Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA1cytosol
a ganglioside GM1b (d18:1(4E))Reach from here →
1. a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL4, ST3GAL2
a ganglioside GD1alpha (d18:1(4E))Reach from here →
1. a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)
Catalysed by ST6GALNAC3, ST6GALNAC6, ST6GALNAC5, ST6GALNAC4
a ganglioside GT1aalpha (d18:1(4E))Reach from here →
1. a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)
Catalysed by ST6GALNAC6
a ganglioside GQ1balpha (d18:1(4E))Reach from here →
1. a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)
Catalysed by ST6GALNAC6
a ganglioside GD3Reach from here →
1. a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD3 + CMP + H(+)
Catalysed by ST8SIA3, ST8SIA6
a ganglioside GT3Reach from here →
1. a ganglioside GD3 + CMP-N-acetyl-beta-neuraminate = a ganglioside GT3 + CMP + H(+)
Catalysed by ST8SIA1
a ganglioside GD1aReach from here →
1. a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramideReach from here →
1. a beta-D-Gal-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)
Catalysed by ST3GAL5
a ganglioside GT1bReach from here →
1. a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1b + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2
a ganglioside GD1b (d18:1(4E))Reach from here →
1. ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by ST8SIA1cytosol
a ganglioside GD1c (d18:1(4E))Reach from here →
1. a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1c (d18:1(4E)) + CMP + H(+)
Catalysed by ST8SIA5, ST8SIA6, ST8SIA1
a ganglioside GQ1c (d18:1(4E))Reach from here →
1. a ganglioside GT1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1c (d18:1(4E)) + CMP + H(+)
Catalysed by ST3GAL4
a ganglioside GP1c (d18:1(4E))Reach from here →
1. a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GP1c (d18:1(4E)) + CMP + H(+)
Catalysed by ST8SIA5
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enineReach from here →
1. N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acyl-sphing-4-enine + CMP + H(+)
Catalysed by ST6GALNAC6, ST6GALNAC5
a ganglioside GM1bReach from here →
1. a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2
ganglioside GD1a (18:1(4E)/18:0)Reach from here →
1. ganglioside GM1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate = ganglioside GD1a (18:1(4E)/18:0) + CMP + H(+)
Catalysed by ST3GAL1, ST3GAL2
a neolactoside IV(3)-alpha-NeuAc-nLc4CerReach from here →
1. a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+)
Catalysed by ST3GAL4
a ganglioside GT1aReach from here →
1. a ganglioside GD1a + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1a + CMP + H(+)
Catalysed by ST8SIA6
a ganglioside GD1cReach from here →
1. a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1c + CMP + H(+)
Catalysed by ST8SIA6
an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+)
Catalysed by ST8SIA6
N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramideReach from here →
1. N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)
Catalysed by ST8SIA6