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Proteins/UNIPROT:Q96JF0
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids..
Function from UniProtKB (Q96JF0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
10 statements
10 statements · 4 reference databases · Subject: ST6GAL2 · Sources: Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
2CMP-N-acetyl-beta-neuraminate+MAM02323g2cytidine 5'-monophosphate+2proton+MAM02672g
Catalysed by ST6GAL1 or ST6GAL2
Reaction pageLeft to rightBalance undeterminableEC 2.4.3.1Golgi apparatus
Human-GEM MAR07334CC BY 4.0Reference data
a beta-D-galactoside+CMP-N-acetyl-beta-neuraminatean N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative+CMP
8 names
Resolves to: ST6GAL2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:52104CC BY 4.0Reference data