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Proteins/UNIPROT:Q8TCU3

SLC7A13

Protein·UNIPROT:Q8TCU3Solute carrier family 7 member 13

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Associates with SLC3A1/rBAT to form a functional heterodimeric complex that transports anionic and neutral amino acids across the apical plasma membrane of renal epithelium. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. May act as a major transporter for L-cystine in late proximal tubules, ensuring its reabsorption from the luminal fluid in exchange for cytosolic L-glutamate or L-aspartate..

Function from UniProtKB (Q8TCU3), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

18 statements

18 statements · 1 reference database · Subject: SLC7A13 · Sources: Rhea

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L-aspartate is transported by SLC7A13CompoundRhea RHEA:76335Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76299Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76307Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76311Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76315Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76319Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76323Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76327Inferred only
L-aspartate is transported by SLC7A13CompoundRhea RHEA:76331Inferred only
L-cystine is transported by SLC7A13CompoundRhea RHEA:76303Inferred only
L-cystine is transported by SLC7A13CompoundRhea RHEA:76299Inferred only
L-glutamine is transported by SLC7A13CompoundRhea RHEA:76311Inferred only

Show the remaining 6

L-leucine is transported by SLC7A13CompoundRhea RHEA:76319Inferred only
L-methionine is transported by SLC7A13CompoundRhea RHEA:76315Inferred only
L-phenylalanine is transported by SLC7A13CompoundRhea RHEA:76327Inferred only
L-tryptophan is transported by SLC7A13CompoundRhea RHEA:76335Inferred only
L-tyrosine is transported by SLC7A13CompoundRhea RHEA:76331Inferred only
L-valine is transported by SLC7A13CompoundRhea RHEA:76323Inferred only

Reactions

10 reactions

L-cystine+L-aspartateL-cystine+L-aspartate
Transported by SLC7A13
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:76299CC BY 4.0Reference data
L-cystineL-cystine
Transported by SLC7A13
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:76303CC BY 4.0Reference data
L-aspartate+

Other names

4 names

Resolves to: SLC7A13

Also called: AGT1Sodium-independent aspartate/glutamate transporter 1X-amino acid transporter 2XAT2

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L-glutamate(1-)

?

+L-glutamate(1-)

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76307CC BY 4.0Reference data

L-aspartate+L-glutamineL-aspartate+L-glutamine

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76311CC BY 4.0Reference data

L-aspartate+L-methionineL-aspartate+L-methionine

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76315CC BY 4.0Reference data

L-leucine+L-aspartateL-leucine+L-aspartate

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76319CC BY 4.0Reference data

L-valine+L-aspartateL-valine+L-aspartate

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76323CC BY 4.0Reference data

L-aspartate+L-phenylalanineL-aspartate+L-phenylalanine

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76327CC BY 4.0Reference data

L-tyrosine+L-aspartateL-tyrosine+L-aspartate

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76331CC BY 4.0Reference data

L-tryptophan+L-aspartateL-tryptophan+L-aspartate

Transported by SLC7A13

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:76335CC BY 4.0Reference data