Compound
guanosine
A purine nucleoside that has guanine linked by its N9 nitrogen to the C1 carbon of ribose. It is a component of ribonucleic acid and its nucleotides play important roles in metabolism. (From Dorland, 28th ed)
Structure
No depiction stored
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- Class
- Organic compound
- Formula
- C10H13N5O5
- Mass
- 283.244 g/mol
- Charge
- 0
- InChIKey
- NYHBQMYGNKIUIF-UUOKFMHZSA-N
- SMILES
- Nc1nc(=O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- SLC29A1ProteinUNIPROT:Q99808transported byInferred only129 paths43 endpoints
- PNPProteinUNIPROT:P00491substrate ofInferred only72 paths36 endpoints
- NT5C2ProteinUNIPROT:P49902substrate ofInferred only12 paths12 endpoints
- SLC29A2ProteinUNIPROT:Q14542transported byInferred only6 paths3 endpoints
- SLC22A7ProteinUNIPROT:Q9Y694transported byInferred only2 paths2 endpoints
What the reference databases state
Chemical structure
- 2'-deoxyguanosine has the functional parent guanosineCompoundChEBI CHEBI:17172Inferred only
- guanosine has the functional parent guanineCompoundChEBI CHEBI:16750Inferred only
Statements
21 statements
21 statements · 2 reference databases · Subject: guanosine · Sources: Human-GEM, Rhea
- xanthosine is converted to guanosineCompoundRhea RHEA:12861Inferred only
- guanosine is converted to xanthosineCompoundHuman-GEM MAR05394Inferred only
- guanosine is converted to xanthosineCompoundRhea RHEA:12861Inferred only
- guanosine is a substrate of LACC1ProteinRhea RHEA:13233Inferred only
- guanosine is a substrate of NT5C2ProteinRhea RHEA:69584Inferred only
- guanosine is a substrate of PNPProteinRhea RHEA:13233Inferred only
- guanosine is a substrate of PNPProteinHuman-GEM MAR04651Inferred only
- guanosine is transported by SLC22A7ProteinRhea RHEA:75371Inferred only
- guanosine is transported by SLC28A2ProteinHuman-GEM MAR05129Inferred only
- guanosine is transported by SLC28A2ProteinRhea RHEA:69935Inferred only
- guanosine is transported by SLC28A3ProteinRhea RHEA:69915Inferred only
- guanosine is transported by SLC28A3ProteinHuman-GEM MAR05129Inferred only
Show the remaining 9
- guanosine is transported by SLC28A3ProteinHuman-GEM MAR06360Inferred only
- guanosine is transported by SLC28A3ProteinHuman-GEM MAR09889Inferred only
- guanosine is transported by SLC29A1ProteinRhea RHEA:75371Inferred only
- guanosine is transported by SLC29A1ProteinHuman-GEM MAR05037Inferred only
- guanosine is transported by SLC29A1ProteinHuman-GEM MAR05036Inferred only
- guanosine is transported by SLC29A2ProteinRhea RHEA:75371Inferred only
- guanosine is transported by SLC29A2ProteinHuman-GEM MAR05037Inferred only
- guanosine is transported by SLC29A3ProteinHuman-GEM MAR07729Inferred only
- guanosine is transported by SLC29A3ProteinRhea RHEA:75371Inferred only
Reactions
27 reactions
GMP+waterguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5cytosol
Human-GEM MAR04449CC BY 4.0Reference data
GMP+waterguanosine+phosphate(3-)
Catalysed by ACP3 or NT5C2 or NT5C1A or NT5C3A or NT5E or NT5C3B or RBAK or NT5C1B or NT5M
Reaction pageLeft to rightBalancedEC 3.1.3.5extracellular space
Human-GEM MAR04450CC BY 4.0Reference data
Reaction pageLeft to rightBalancedEC 2.7.1.73mitochondrial matrix
Human-GEM MAR04451CC BY 4.0Reference data
guanosine+phosphate(3-)guanine+D-ribose 1-phosphate
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.15, 2.4.2.1cytosol
Human-GEM MAR04651CC BY 4.0Reference data
Transported by SLC29A1
Reaction pageLeft to rightBalancedmitochondrial matrix, cytosol
Human-GEM MAR05036CC BY 4.0Reference data
Transported by SLC29A1 or SLC29A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05037CC BY 4.0Reference data
guanosine+sodium(1+)guanosine+sodium(1+)
Transported by SLC28A2 or SLC28A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05129CC BY 4.0Reference data
guanosine+waterammonium+xanthosine
Reaction pageLeft to rightBalancedEC 3.5.4.15cytosol
Human-GEM MAR05394CC BY 4.0Reference data
guanosine+2sodium(1+)guanosine+2sodium(1+)
Transported by SLC28A3
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06360CC BY 4.0Reference data
GMP+waterguanosine+phosphate(3-)
Catalysed by NT5C2 or NT5C1A or NT5C3A or NT5C or NT5E or NT5C3B or NT5C1B
Reaction pageLeft to rightBalancedEC 3.1.3.5lysosome
Human-GEM MAR07728CC BY 4.0Reference data
Transported by SLC29A3
Reaction pageReversibleBalancedcytosol, lysosome
Human-GEM MAR07729CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09348CC BY 4.0Reference data
On the label
Labelled products
3 products
Source: NIH DSLD · Ingredient: guanosine · 3 products · Declared amount per serving: 80–80 mg (2 products)
2 labels state an amount1 does not
- BluebonnetNucleotide Complex80 mgper 1 Capsule(s)DSLD:268367
- BluebonnetNucleotide Complex 50080 mgper 1 Capsule(s)DSLD:179326
- Premier Research LabsNucleo Immuneamount not statedper 3 Capsule(s)DSLD:297553
Label record: NIH Office of Dietary Supplements · CC0
Where it reaches
6 systems, 15 regions, 43 tissues, 45 transporter routes — routes, not measurements: transporters known to carry guanosine are expressed there, and no source reports it arriving.
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Other names
13 names
Resolves to: guanosine
- Also called
- 2-amino-1,9-dihydro-9-beta-D-ribofuranosyl-6H-purin-6-one2-amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one2-amino-9-beta-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one2-amino-9-β-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one2(3H)-imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one2(3H)-imino-9-β-D-ribofuranosyl-9H-purin-6(1H)-one9-beta-D-ribofuranosyl-guanine9-β-D-ribofuranosyl-guanineGuanine ribosideGuanine-9-beta-D-ribofuranosideGuanine-9-β-D-ribofuranosideGuanosinGuo