Compound
2'-deoxyinosine
A purine 2'-deoxyribonucleoside that is inosine in which the hydroxy group at position 2' is replaced by a hydrogen.
Definition from ChEBI (CHEBI:28997), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
Loading the model…
- Class
- Organic compound
- Formula
- C10H12N4O4
- Mass
- 252.23 g/mol
- Charge
- 0
- InChIKey
- VGONTNSXDCQUGY-RRKCRQDMSA-N
- SMILES
- O=c1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Chemical structure
- 2'-deoxyinosine has the functional parent inosineCompoundChEBI CHEBI:28997Inferred only
Statements
11 statements
11 statements · 2 reference databases · Subject: 2'-deoxyinosine · Sources: Human-GEM, Rhea
- 2'-deoxyadenosine is converted to 2'-deoxyinosineCompoundHuman-GEM MAR04694Inferred only
- 2'-deoxyadenosine is converted to 2'-deoxyinosineCompoundHuman-GEM MAR08473Inferred only
- dIMP is converted to 2'-deoxyinosineCompoundHuman-GEM MAR07880Inferred only
- 2'-deoxyinosine is a substrate of NT5C2ProteinRhea RHEA:69572Inferred only
- 2'-deoxyinosine is a substrate of PNPProteinRhea RHEA:27750Inferred only
- 2'-deoxyinosine is a substrate of PNPProteinHuman-GEM MAR04709Inferred only
- 2'-deoxyinosine is transported by SLC28A2ProteinHuman-GEM MAR06354Inferred only
- 2'-deoxyinosine is transported by SLC28A3ProteinHuman-GEM MAR06354Inferred only
- 2'-deoxyinosine is transported by SLC28A3ProteinHuman-GEM MAR06365Inferred only
- 2'-deoxyinosine is transported by SLC29A1ProteinHuman-GEM MAR06369Inferred only
- 2'-deoxyinosine is transported by SLC29A2ProteinHuman-GEM MAR06369Inferred only
Reactions
13 reactions
2'-deoxyadenosine+water2'-deoxyinosine+ammonium
Reaction pageLeft to rightBalancedEC 3.5.4.4GO:0005829
Human-GEM MAR04694CC BY 4.0Reference data
MAM00639c+hypoxanthine2'-deoxyinosine+phosphate(3-)
Catalysed by PNP
Reaction pageReversibleBalancedEC 2.4.2.1, 2.4.2.4GO:0005829
Human-GEM MAR04709CC BY 4.0Reference data
2'-deoxyinosine+sodium(1+)2'-deoxyinosine+sodium(1+)
Transported by SLC28A2 or SLC28A3
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR06354CC BY 4.0Reference data
2'-deoxyinosine+2sodium(1+)2'-deoxyinosine+2sodium(1+)
Transported by SLC28A3
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR06365CC BY 4.0Reference data
2'-deoxyinosine2'-deoxyinosine
Transported by SLC29A1 or SLC29A2
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR06369CC BY 4.0Reference data
dIMP+water2'-deoxyinosine+phosphate(3-)
Catalysed by NT5C
Reaction pageLeft to rightBalancedEC 3.1.3.-GO:0005829
Human-GEM MAR07880CC BY 4.0Reference data
2'-deoxyadenosine+water2'-deoxyinosine+ammonium
Catalysed by ADA
Reaction pageLeft to rightBalancedEC 3.5.4.4GO:0005615
Human-GEM MAR08473CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09305CC BY 4.0Reference data
2'-deoxyinosine+hydrogenphosphate2-deoxy-alpha-D-ribose 1-phosphate+hypoxanthine
Catalysed by PNP
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:27750CC BY 4.0Reference data
2'-deoxyadenosine+water+hydron2'-deoxyinosine+ammonium
Catalysed by ADA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:28190CC BY 4.0Reference data
dIMP+water2'-deoxyinosine+hydrogenphosphate
Catalysed by NT5C2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:29383CC BY 4.0Reference data
2'-deoxyinosine+hydron2'-deoxyinosine+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:29971CC BY 4.0Reference data
Where it reaches
6 systems, 14 regions, 41 tissues, 43 transporter routes — routes, not measurements: transporters known to carry 2'-deoxyinosine are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: 2'-deoxyinosine
- Also called
- 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-olDeoxyinosine
- Systematic name
- 9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-9H-purin-6-ol