(6Z,9Z,12Z)-octadecatrienoyl-CoA

1. Gamma-linolenoyl-CoA hydrolase

Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 1 morecytosolOne of 10 routes

1. (6Z,9Z,12Z)-octadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

Catalysed by ACADL, ACADVL, ACAD9One of 2 routes

1. Beta Oxidation of Fatty Acid

Catalysed by ACADM, ACADSmitochondrial matrixOne of 2 routes

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. (6Z,9Z,12Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(8Z,11Z,14Z)-eicosatrienoyl-CoA + CO2 + CoA

Catalysed by ELOVL7, ELOVL5

1. fatty-acyl-CoA elongation (N-C18:3CoA)

Catalysed by ELOVL4, ELOVL6, ELOVL2, ELOVL5cytosolOne of 2 routes

1. Gamma-linolenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 4 morecytosolOne of 244 routes

1. Beta Oxidation of Fatty Acid
2. octanoyl-CoA + H2O = S-octanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by ACADM, ACADS, NUDT19, NUDT7 and 1 more