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Proteins/UNIPROT:Q9HCC0
Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism..
Function from UniProtKB (Q9HCC0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
46 statements
46 statements · 5 reference databases · Subject: MCCC2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
4 reactions
3-methylbut-2-enoyl-CoA+ATP+hydrogencarbonate3-methyl-(2E)-glutaconyl-CoA+ADP+proton+phosphate(3-)
Reaction pageLeft to rightBalancedEC 6.4.1.4mitochondrial matrix
Human-GEM MAR03773CC BY 4.0Reference data
MAM00667m+ADP+proton+phosphate(3-)
5 names
Resolves to: MCCC2
Reaction pageReversibleBalancedEC 6.4.1.4mitochondrial matrix
Human-GEM MAR06926CC BY 4.0Reference data
MAM00666m+CHEBI:1146900+protonMAM00667m+water
Reaction pageReversibleBalancedEC 6.4.1.4mitochondrial matrix
Human-GEM MAR06927CC BY 4.0Reference data
3-methylbut-2-enoyl-CoA+hydrogencarbonate+ATP(4-)3-methyl-(2E)-glutaconyl-CoA+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13589CC BY 4.0Reference data