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Proteins/UNIPROT:P11117
Lysosomal acid phosphatase that catalyzes the hydrolysis of orthophosphoric monoesters to alcohols and phosphate under acidic conditions (Probable). May contribute to the removal of mannose-6-phosphate (Man6P) from lysosomal proteins after their delivery to lysosomes, acting in concert with ACP5 (By similarity)..
(Microbial infection) Plays a crucial role in the membrane fusion step of the influenza A and B viruses entry process..
Function from UniProtKB (P11117), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
15 statements
15 statements · 6 reference databases · Subject: ACP2 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Rhea, WikiPathways
7 reactions
water+MAM03200ladenosine+phosphate(3-)
Catalysed by ACP3 or ACP5 or ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2lysosome
Human-GEM MAR00046CC BY 4.0Reference data
CHEBI:1146900+water3'-dephospho-CoA+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to right
2 names
Resolves to: ACP2
Human-GEM MAR07731CC BY 4.0Reference data
dCMP+water2'-deoxycytidine+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2lysosome
Human-GEM MAR08493CC BY 4.0Reference data
MAM01639l+water2'-deoxyadenosine+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2lysosome
Human-GEM MAR08494CC BY 4.0Reference data
dGMP+water2'-deoxyguanosine+phosphate(3-)
Catalysed by ACP2
Reaction pageLeft to rightBalancedEC 3.1.3.2lysosome
Human-GEM MAR08495CC BY 4.0Reference data
MAM01020e+waterphosphate(3-)+4-nitrophenol
Catalysed by ACP3 or ACP5 or ACP2 or ACP4 or PXYLP1 or ALPL or ACP6 or ALPP or ALPG or ALPI
Reaction pageLeft to rightBalancedEC 3.1.3.1, 3.1.3.2, 3.1.3.41extracellular space
Human-GEM MAR09569CC BY 4.0Reference data
a phosphate monoester+wateran alcohol+hydrogenphosphate
Catalysed by ALPL or ALPP or ALPI or ALPG or ACP2 or ACP5 or ACP3 or ACP1 or ACP7
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:15017CC BY 4.0Reference data