Compound
CHEBI:28701
A choloyl-CoA formed by thioester linkage between chenodeoxycholic acid and coenzyme A.
Definition from ChEBI (CHEBI:28701), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- BAATProteinUNIPROT:Q14032substrate ofInferred only114 paths19 endpoints
- ACOT2ProteinUNIPROT:P49753substrate ofInferred only22 paths22 endpoints
- SCP2ProteinUNIPROT:P22307substrate ofInferred only21 paths21 endpoints
- ACOT8ProteinUNIPROT:O14734substrate ofInferred only16 paths16 endpoints
- ACOT7ProteinUNIPROT:O00154substrate ofInferred only12 paths6 endpoints
- ACOT4ProteinUNIPROT:Q8N9L9substrate ofInferred only9 paths9 endpoints
- ACOT1ProteinUNIPROT:Q86TX2substrate ofInferred only8 paths8 endpoints
What the reference databases state
Statements
13 statements
13 statements · 1 reference database · Subject: CHEBI:28701 · Sources: Human-GEM
- CHEBI:28701 is a substrate of ACOT1ProteinHuman-GEM MAR01716Inferred only
- CHEBI:28701 is a substrate of ACOT2ProteinHuman-GEM MAR02940Inferred only
- CHEBI:28701 is a substrate of ACOT4ProteinHuman-GEM MAR01718Inferred only
- CHEBI:28701 is a substrate of ACOT7ProteinHuman-GEM MAR01716Inferred only
- CHEBI:28701 is a substrate of ACOT7ProteinHuman-GEM MAR02940Inferred only
- CHEBI:28701 is a substrate of ACOT8ProteinHuman-GEM MAR01718Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR00085Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR01716Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR01718Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR01720Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR01722Inferred only
- CHEBI:28701 is a substrate of BAATProteinHuman-GEM MAR01723Inferred only
Show the remaining 1
- CHEBI:28701 is a substrate of SCP2ProteinHuman-GEM MAR02950Inferred only
Reactions
15 reactions
CHEBI:28701+glycineCHEBI:1146900+glycochenodeoxycholic acid
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005777
Human-GEM MAR00085CC BY 4.0Reference data
MAM00754x+CHEBI:1146900CHEBI:28701+propionyl-CoA
Catalysed by ACAA1 or SCP2 or MYO5B
Reaction pageLeft to rightBalancedEC 2.3.1.176GO:0005777
Human-GEM MAR01710CC BY 4.0Reference data
CHEBI:28701+waterchenodeoxycholate+CHEBI:1146900+proton
Catalysed by ACOT1 or ACOT7 or BAAT
Reaction pageLeft to rightBalancedEC 3.1.2.2GO:0005777
Human-GEM MAR01716CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005829, GO:0005777
Human-GEM MAR01717CC BY 4.0Reference data
CHEBI:28701+waterchenodeoxycholate+CHEBI:1146900+proton
Catalysed by ACOT4 or ACOT8 or BAAT
Reaction pageLeft to rightBalancedEC 3.1.2.2GO:0005829
Human-GEM MAR01718CC BY 4.0Reference data
CHEBI:28701+taurineCHEBI:1146900+taurochenodeoxycholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005777
Human-GEM MAR01720CC BY 4.0Reference data
CHEBI:28701+glycineCHEBI:1146900+glycochenodeoxycholic acid
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005829
Human-GEM MAR01722CC BY 4.0Reference data
CHEBI:28701+taurineCHEBI:1146900+taurochenodeoxycholate
Catalysed by BAAT
Reaction pageLeft to rightBalancedEC 2.3.1.65GO:0005829
Human-GEM MAR01723CC BY 4.0Reference data
Reaction pageReversibleBalancedGO:0005829, GO:0005783
Human-GEM MAR01725CC BY 4.0Reference data
ATP+chenodeoxycholate+CHEBI:1146900AMP+CHEBI:28701+diphosphate(3-)
Catalysed by SLC27A5
Reaction pageLeft to rightBalancedEC 6.2.1.7GO:0005829
Human-GEM MAR01726CC BY 4.0Reference data
ATP+chenodeoxycholate+CHEBI:1146900AMP+CHEBI:28701+diphosphate(3-)
Catalysed by SLC27A5 or SLC27A2
Reaction pageLeft to rightBalancedEC 6.2.1.7GO:0005783
Human-GEM MAR01727CC BY 4.0Reference data
CHEBI:28701+waterchenodeoxycholate+CHEBI:1146900+proton
Reaction pageReversibleBalancedEC 3.1.2.2GO:0005759
Human-GEM MAR02940CC BY 4.0Reference data
Other names
5 names
Resolves to: CHEBI:28701
- Also called
- 3alpha,7alpha-Dihydroxy-5beta-cholanoyl-CoAChenodeoxycholoyl-CoAchenodeoxycholoyl-coenzyme A
- Systematic name
- 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3alpha,7alpha-dihydroxy-5beta-cholan-24-oyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(3α,7α-dihydroxy-5β-cholan-24-oyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}