5-methylsulfanyl-2,3-dioxopentyl phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

138 compounds within 3 steps: 3 in 1, 17 in 2, 118 in 3

One step

formic acidReach from here →
1. 2, 3-Diketo-5-Methylthio-1-Phosphopentane Degradation Reaction
No catalyst recordedcytosol
4-methylthio-2-oxobutanoic acidReach from here →
1. 2, 3-Diketo-5-Methylthio-1-Phosphopentane Degradation Reaction
No catalyst recordedcytosol
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-oneReach from here →
1. Acireductone Synthase
Catalysed by ENOPH1cytosolOne of 2 routes

Two steps

2-hydroxybutyric acidReach from here →
1. 2, 3-Diketo-5-Methylthio-1-Phosphopentane Degradation Reaction
2. transport of 2-hydroxybutyrate and formate (cytosol to extracellular)
Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A1cytosol, extracellular spaceOne of 2 routes
acetoacetateReach from here →
1. 2, 3-Diketo-5-Methylthio-1-Phosphopentane Degradation Reaction
2. transport of acetoacetate and formate (cytosol to extracellular)
Catalysed by SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

Three steps

3-(methylthio)propionic acidReach from here →

Catalysed by ENOPH1, ADI1cytosol

pyruvateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A8 and 1 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinoic acidReach from here →

Catalysed by SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

10-formyltetrahydrofolic acidReach from here →

Catalysed by MTHFD1cytosolOne of 2 routes

formateReach from here →

Catalysed by ENOPH1, ADI1cytosolOne of 2 routes

4-methylsulfanyl-2-oxobutanoateReach from here →

Catalysed by ENOPH1, ADI1cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A1cytosol, extracellular spaceOne of 2 routes

COReach from here →

Catalysed by ENOPH1, ADI1cytosolOne of 2 routes

chlorine(.)Reach from here →

Catalysed by SLC26A4cytosol, extracellular spaceOne of 2 routes

acetateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

(S)-lactic acidReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

3-(methylsulfanyl)propanoateReach from here →

Catalysed by ENOPH1, ADI1cytosol

L-methionineReach from here →

Catalysed by TATcytosolOne of 2 routes

SLC26A4

, SLC6A14

cytosol, extracellular space

CHEBI:1146900Reach from here →

Catalysed by TAT, NAGScytosol, mitochondrial matrix

prostaglandin E3Reach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

prostaglandin A2Reach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

prostaglandin J2Reach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

15-oxoprostaglandin F2alphaReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A3, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

all-trans-4-hydroxyretinoateReach from here →

Catalysed by SLC16A4, SLC16A5, CYP26A1cytosol, extracellular spaceOne of 3 routes

N-acetylcadaverineReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A1, HDAC10cytosol, extracellular space

all-trans-retinoyl-1-O-(beta-D-glucuronate)Reach from here →

Catalysed by SLC16A4, SLC16A5, UGT1A1, UGT1A10 and 1 morecytosol, extracellular space, endoplasmic reticulum

all-trans-18-hydroxyretinoateReach from here →

Catalysed by SLC16A4, SLC16A5, CYP1A1, CYP1A2 and 23 morecytosol, extracellular spaceOne of 2 routes

a phenyl acetateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A1, PON1 and 2 morecytosol, extracellular space

CHEBI:15345Reach from here →

Catalysed by SLC16A4, SLC16A5, AACScytosol, extracellular spaceOne of 3 routes

acetoneReach from here →

Catalysed by SLC16A4, SLC16A5cytosol, extracellular space, mitochondrial matrix

cholineReach from here →

Catalysed by SLC26A4, SLC5A7cytosol, extracellular space

acetylpyruvateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A8 and 2 morecytosol, extracellular spaceOne of 2 routes

propionyl-CoAReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A1, ACSS3 and 2 morecytosol, extracellular spaceOne of 3 routes

(S)-malateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A8 and 2 morecytosol, extracellular spaceOne of 2 routes

L-leucineReach from here →

Catalysed by TAT, SLC3A2, SLC7A5cytosol, extracellular spaceOne of 8 routes

CHEBI:15699Reach from here →

Catalysed by TAT, SLC7A5cytosol, extracellular spaceOne of 3 routes

CHEBI:15971Reach from here →

Catalysed by TAT, SLC7A6cytosol, extracellular spaceOne of 3 routes

methanethiolReach from here →

Catalysed by ENOPH1, ADI1cytosol

sulfateReach from here →

Catalysed by SLC26A4, SLC26A6cytosol, extracellular space

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A8 and 2 morecytosol, extracellular space, mitochondrial matrix

L-citrullineReach from here →

Catalysed by TAT, SLC7A6cytosol, extracellular spaceOne of 2 routes

iodideReach from here →

Catalysed by SLC26A4cytosol, extracellular space

L-valineReach from here →

Catalysed by TAT, SLC7A5cytosol, extracellular spaceOne of 5 routes

oxaloacetateReach from here →

Catalysed by SLC16A4, SLC16A5, SLC16A7, SLC16A8 and 2 morecytosol, extracellular space, mitochondrial matrixOne of 3 routes

L-arginineReach from here →

Catalysed by TAT, SLC7A6cytosol, extracellular spaceOne of 7 routes

protein polypeptide chainReach from here →

Catalysed by TATcytosol