CO

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

30 compounds within 3 steps: 2 in 1, 8 in 2, 20 in 3

One step

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-oneReach from here →
1. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
Catalysed by ADI1
quercetinReach from here →
1. quercetin + O2 = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO
Catalysed by PIR

Two steps

3-(methylthio)propionic acidReach from here →
1. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
2. acireductone dioxygenase
Catalysed by ADI1cytosol
formateReach from here →
1. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
2. 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)
Catalysed by ADI1One of 2 routes
4-methylsulfanyl-2-oxobutanoateReach from here →

Three steps

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)

Catalysed by ADI1

formic acidReach from here →

Catalysed by ADI1cytosolOne of 2 routes

4-methylthio-2-oxobutanoic acidReach from here →

Catalysed by ADI1cytosol

3-(methylsulfanyl)propanoateReach from here →

Catalysed by ADI1

2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoateReach from here →

Catalysed by PIR

5-methylsulfanyl-2,3-dioxopentyl phosphateReach from here →

Catalysed by ADI1, ENOPH1

Catalysed by ADI1, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

pyruvateReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinoic acidReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

10-formyltetrahydrofolic acidReach from here →

Catalysed by ADI1, MTHFD1cytosolOne of 2 routes

methanethiolReach from here →

Catalysed by ADI1cytosol

formaldehydeReach from here →

Catalysed by ADI1, ALDH9A1

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes

(6R)-10-formyltetrahydrofolateReach from here →

Catalysed by ADI1, MTHFD1, MTHFD1L

chlorine(.)Reach from here →

Catalysed by ADI1, SLC26A4cytosol, extracellular spaceOne of 2 routes

acetateReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

oxalateReach from here →

Catalysed by ADI1, SLC26A6inner side of the membrane, outer side of the membraneOne of 2 routes

propionic acidReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

glyoxylateReach from here →

Catalysed by ADI1, AADAT

(S)-lactic acidReach from here →

Catalysed by ADI1, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

S-formylglutathioneReach from here →

Catalysed by ADI1, ESD

L-methionineReach from here →

Catalysed by ADI1, TATcytosolOne of 4 routes

kynurenateReach from here →

Catalysed by ADI1, AADAT

N-formyl-L-kynurenineReach from here →

Catalysed by ADI1, AFMID