UDP-N-acetyl-alpha-D-glucosamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

139 compounds within 3 steps: 12 in 1, 52 in 2, 75 in 3

Three steps

a fatty acidReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a globoside Gb3Cer (d18:1(4E)) + UDP + H(+)
3. a globoside Gb3Cer (d18:1(4E)) + H2O = a lysoGb3(d18:1(4E)) + a fatty acid
Catalysed by SLC35A2, A4GALT, ASAH1inner side of the membrane, outer side of the membraneOne of 2 routes
N-glycoloylneuraminateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
3. CMP-N-acetylneuraminate monooxygenase (N-acetylneuraminate)
Catalysed by GNE, NPLcytosol
formic acidReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. transport of acetate and formate (cytosol to extracellular)
Catalysed by PIGA, PIGL, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes
propionic acidReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. transport of acetate and propanoate (cytosol to extracellular)
Catalysed by PIGA, PIGL, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes
butyric acidReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. transport of acetate and butyrate (cytosol to extracellular)
Catalysed by PIGA, PIGL, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes
N-acetylneuraminateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
2. a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + UDP + H(+)
3. a ganglioside GM2 (d18:1(4E)) + H2O = a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate
Catalysed by GALE, B4GALNT1, NEU4, NEU3One of 5 routes
D-galactoseReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a globoside Gb3Cer (d18:1(4E)) + UDP + H(+)
3. a globoside Gb3Cer (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose
Catalysed by SLC35A2, A4GALT, GLAinner side of the membrane, outer side of the membraneOne of 4 routes
D-glucoseReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)
3. lactose + H2O = beta-D-galactose + D-glucose
Catalysed by SLC35A2, B4GALT2, B4GALT1, LCTinner side of the membrane, outer side of the membrane
(S)-lactic acidReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. transport of acetate and L-lactate (cytosol to extracellular)
Catalysed by PIGA, PIGL, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes
daidzein 7-O-beta-D-glucosideReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. daidzein + UDP-alpha-D-glucose = daidzein 7-O-beta-D-glucoside + UDP
Catalysed by SLC35A2, GALT, UGT3A2inner side of the membrane, outer side of the membrane
N-(acetyl)-sphing-4-enineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
Catalysed by PIGA, PIGL, ASAH1endoplasmic reticulum
an N-acylsphing-4-enineReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = D-galactose + an N-acylsphing-4-enine
Catalysed by SLC35A2, UGT8, GBA1, GALC and 2 moreinner side of the membrane, outer side of the membraneOne of 2 routes
CMP-N-acetyl-beta-neuraminateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine + H2O = aldehydo-N-acetyl-D-mannosamine + UDP + H(+)
2. N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)
3. CTP:N-acetylneuraminate cytidylyltransferase
Catalysed by GNE, NPL, CMAScytosol, nucleusOne of 2 routes
N-acetylputrescineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. N-acetylputrescine + H2O = putrescine + acetate
Catalysed by PIGA, PIGL, HDAC10endoplasmic reticulum
N(8)-acetylspermidineReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. N(8)-acetylspermidine + H2O = spermidine + acetate
Catalysed by PIGA, PIGL, HDAC10endoplasmic reticulum
alpha-D-glucose 1-phosphateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
Catalysed by SLC35A2, GALTinner side of the membrane, outer side of the membraneOne of 3 routes
a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E))Reach from here →
1. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)
2. beta-1,4-galactosyltransferase (lc3Cer)
3. ST3 beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosolOne of 2 routes
an N-acetyl-L-cysteine-S-conjugateReach from here →
1. a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + UDP + H(+)
2. phosphatidylinositol glycan anchor biosynthesis class L
3. an N-acetyl-L-cysteine-S-conjugate + H2O = an S-substituted L-cysteine + acetate
Catalysed by PIGA, PIGL, ACY3endoplasmic reticulum
D-glucosamine 6-phosphateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-alpha-D-glucosamine 1-phosphate + UMP + 2 H(+)
2. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
3. D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)
Catalysed by ENPP3, PGM3, GNPNAT1One of 2 routes
a ganglioside GM3 (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
2. a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 (d18:1(4E)) + UDP + H(+)
3. beta-N-acetylhexosaminidase (GM2)
Catalysed by GALE, B4GALNT1, HEXA, HEXB and 1 morecytosolOne of 7 routes
CHEBI:67119Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
3. UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase
Catalysed by SLC35A2, GALTinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes
2-acetamido-2-deoxy-D-glucopyranose 1-phosphateReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine + H2O = N-acetyl-alpha-D-glucosamine 1-phosphate + UMP + 2 H(+)
2. N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate
3. phosphoglucomutase (N-acetylglucosamine-6-phosphate)
Catalysed by ENPP3, PGM3cytosol
an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enineReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + 3'-phosphoadenylyl sulfate = an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
Catalysed by SLC35A2, UGT8, GAL3ST1inner side of the membrane, outer side of the membrane
a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E))Reach from here →
1. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)
2. beta-1,4-galactosyltransferase (lc3Cer)
3. a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)
Catalysed by B3GNT5, B4GALT3, B4GALT4, B4GALT2 and 2 morecytosol
beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enineReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+)
3. a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)
Catalysed by SLC35A2, B4GALT5, B4GALT6, GAL3ST1inner side of the membrane, outer side of the membrane
a ganglioside GD3 (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
2. a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + UDP + H(+)
3. Hexosaminidase A, Lysosomal
Catalysed by GALE, B4GALNT1, HEXA, HEXBlysosome
a ganglioside GD1a (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by SLC35A2, B3GALT4, ST3GAL1, ST3GAL4 and 1 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes
a ganglioside GT1b (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GD1b (d18:1(4E)) + UDP + H(+)
3. beta-galactoside alpha-2,3-sialyltransferase (CMP-N-acetylneuraminate)
Catalysed by SLC35A2, B3GALT4, ST3GAL1, ST3GAL4 and 1 moreinner side of the membrane, outer side of the membrane, cytosolOne of 3 routes
a ganglioside GM4 (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)
3. a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)
Catalysed by SLC35A2, UGT8, ST3GAL5inner side of the membrane, outer side of the membrane
a ganglioside GM1b (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + UDP + H(+)
3. a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)
Catalysed by SLC35A2, B3GALT4, ST3GAL1, ST3GAL4 and 1 moreinner side of the membrane, outer side of the membrane
a ganglioside Fuc-GM1 (d18:1(4E))Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)
3. a ganglioside GM1 (d18:1(4E)) + GDP-beta-L-fucose = a ganglioside Fuc-GM1 (d18:1(4E)) + GDP + H(+)
Catalysed by SLC35A2, B3GALT4, FUT2inner side of the membrane, outer side of the membrane
a ganglioside GM3Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-galactosamine
2. a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + UDP + H(+)
3. a ganglioside GM2 + H2O = a ganglioside GM3 + N-acetyl-beta-D-galactosamine
Catalysed by GALE, B4GALNT1, HEXA, HEXB
a ganglioside GD1aReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)
Catalysed by SLC35A2, B3GALT4, ST3GAL1, ST3GAL2inner side of the membrane, outer side of the membrane
N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramideReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. a beta-D-Gal-(1<->1')-ceramide + CMP-N-acetyl-beta-neuraminate = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide + CMP + H(+)
Catalysed by SLC35A2, UGT8, ST3GAL5inner side of the membrane, outer side of the membrane
1-(3-O-sulfo-beta-D-galactosyl)-ceramideReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. a beta-D-Gal-(1<->1')-ceramide + 3'-phosphoadenylyl sulfate = 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)
Catalysed by SLC35A2, UGT8, GAL3ST1inner side of the membrane, outer side of the membrane
an N-acyl-sphingoid baseReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
3. an N-acyl-sphingoid base + UDP-alpha-D-galactose = a beta-D-Gal-(1<->1')-ceramide + UDP + H(+)
Catalysed by SLC35A2, UGT8inner side of the membrane, outer side of the membrane
a ganglioside GA1Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + H2O = a ganglioside GA1 + N-acetylneuraminate
Catalysed by SLC35A2, B3GALT4, NEU3, NEU2inner side of the membrane, outer side of the membrane
beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucoseReach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. D-glucose + UDP-alpha-D-galactose = lactose + UDP + H(+)
3. lactose + GDP-beta-L-fucose = beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucose + GDP + H(+)
Catalysed by SLC35A2, B4GALT2, B4GALT1, FUT3 and 1 moreinner side of the membrane, outer side of the membrane
a ganglioside Fuc-GM1Reach from here →
1. UDP-N-acetyl-alpha-D-glucosamine(out) + UDP-alpha-D-galactose(in) = UDP-N-acetyl-alpha-D-glucosamine(in) + UDP-alpha-D-galactose(out)
2. a ganglioside GM2 + UDP-alpha-D-galactose = a ganglioside GM1 + UDP + H(+)
3. a ganglioside GM1 + GDP-beta-L-fucose = a ganglioside Fuc-GM1 + GDP + H(+)
Catalysed by SLC35A2, B3GALT4, FUT1, FUT2inner side of the membrane, outer side of the membrane