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2-acetamido-2-deoxy-D-glucopyranose 1-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

12 compounds within 3 steps: 1 in 1, 3 in 2, 8 in 3

Does it reach a compound?

One step

CHEBI:16264Reach from here →
1. UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
Catalysed by UAP1, UAP1L1cytosol

Two steps

a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
1. UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
2. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)
Catalysed by UAP1, UAP1L1, B3GNT5cytosolOne of 2 routes
aldehydo-N-acetyl-D-mannosamineReach from here →
1. UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
2. UDP-N-acetyl-D-glucosamine 2-epimerase
Catalysed by UAP1, UAP1L1, GNEcytosol, endoplasmic reticulumOne of 2 routes

Three steps

a neolactoside nLc4Cer(d18:1(4E))Reach from here →
Catalysed by UAP1, UAP1L1, B3GNT5, B4GALT3 and 3 morecytosolOne of 2 routes
a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E))Reach from here →
1. UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
2. UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase (LacCer pool)

a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol

Reach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
phosphatidylinositol N-acetylglucosaminyltransferase (PI pool)

Catalysed by UAP1, UAP1L1, PIGA, PIGP and 5 morecytosol, endoplasmic reticulumOne of 2 routes

N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase (lc3Cer)

Catalysed by UAP1, UAP1L1, B3GNT5, B3GALT2 and 2 morecytosolOne of 3 routes

aceneuramateReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
UDP-N-acetyl-D-glucosamine 2-epimerase
aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate

Catalysed by UAP1, UAP1L1, GNE, NPLcytosol, endoplasmic reticulum

acetateReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
phosphatidylinositol N-acetylglucosaminyltransferase (PI pool)
phosphatidylinositol glycan anchor biosynthesis class L

Catalysed by UAP1, UAP1L1, PIGA, PIGP and 6 morecytosol, endoplasmic reticulumOne of 3 routes

N-acetyl-beta-neuraminic acidReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
UDP-N-acetyl-D-glucosamine 2-epimerase
N-Acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)

Catalysed by UAP1, UAP1L1, GNE, NPLcytosol, endoplasmic reticulum

N-acetyl-D-glucosamineReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
UDP-N-acetyl-D-glucosamine 2-epimerase
N-acetyl-D-glucosamine 2-epimerase

Catalysed by UAP1, UAP1L1, GNE, RENBPcytosol, endoplasmic reticulum

a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
phosphatidylinositol N-acetylglucosaminyltransferase (PI pool)
phosphatidylinositol glycan anchor biosynthesis class L

Catalysed by UAP1, UAP1L1, PIGA, PIGP and 6 morecytosol, endoplasmic reticulumOne of 3 routes

aldehydo-N-acetyl-D-mannosamine 6-phosphateReach from here →

UDP-N-acetylglucosamine diphosphorylase (N-acetylglucosamine-1-phosphate)
UDP-N-acetyl-D-glucosamine 2-epimerase
ATP:N-acyl-D-mannosamine 6-phosphotransferase

Catalysed by UAP1, UAP1L1, GNEcytosol, endoplasmic reticulumOne of 2 routes