Compound
UDP-N-acetyl-alpha-D-glucosamine
Dianion of UDP-N-acetyl-α-D-glucosamine arising from deprotonation of both free diphosphate OH groups; major species at pH 7.3.
Definition from ChEBI (CHEBI:57705), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
Loading the model…
- Class
- Organic compound, anion
- Formula
- C17H25N3O17P2
- Mass
- 605.339 g/mol
- Charge
- -2
- InChIKey
- LFTYTUAZOPRMMI-CFRASDGPSA-L
- SMILES
- CC(=O)N[C@H]1[C@@H](OP(=O)([O-])OP(=O)([O-])OC[C@H]2O[C@@H](n3ccc(=O)nc3=O)[C@H](O)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
40 entities
40 entities reached.
0 reported hops40 assembled from the scaffold
- MGAT4AProteinUNIPROT:Q9UM21substrate ofInferred only105 paths15 endpoints
- MGAT4BProteinUNIPROT:Q9UQ53substrate ofInferred only95 paths14 endpoints
- OGTProteinUNIPROT:O15294substrate ofInferred only56 paths28 endpoints
- LFNGProteinUNIPROT:Q8NES3substrate ofInferred only40 paths20 endpoints
- B3GNT3ProteinUNIPROT:Q9Y2A9substrate ofInferred only38 paths13 endpoints
- MGAT1ProteinUNIPROT:P26572substrate ofInferred only38 paths19 endpoints
- B3GNT5ProteinUNIPROT:Q9BYG0substrate ofInferred only26 paths13 endpoints
- GCNT3ProteinUNIPROT:O95395substrate ofInferred only25 paths5 endpoints
- MGAT3ProteinUNIPROT:Q09327substrate ofInferred only24 paths8 endpoints
- EXT2ProteinUNIPROT:Q93063substrate ofInferred only24 paths23 endpoints
- GCNT1ProteinUNIPROT:Q02742substrate ofInferred only20 paths5 endpoints
- MGAT2ProteinUNIPROT:Q10469substrate ofInferred only20 paths20 endpoints
Show the remaining 28
- A4GNTProteinUNIPROT:Q9UNA3substrate ofInferred only20 paths4 endpoints
- MGAT5BProteinUNIPROT:Q3V5L5substrate ofInferred only18 paths6 endpoints
- EXTL3ProteinUNIPROT:O43909substrate ofInferred only18 paths18 endpoints
- MFNGProteinUNIPROT:O00587substrate ofInferred only16 paths8 endpoints
- MGAT4CProteinUNIPROT:Q9UBM8substrate ofInferred only15 paths15 endpoints
- DPAGT1ProteinUNIPROT:Q9H3H5substrate ofInferred only14 paths14 endpoints
- MGAT5ProteinUNIPROT:Q09328substrate ofInferred only13 paths13 endpoints
- ALG13ProteinUNIPROT:Q9NP73substrate ofInferred only12 paths12 endpoints
- EXTL2ProteinUNIPROT:Q9UBQ6substrate ofInferred only11 paths11 endpoints
- GNEProteinUNIPROT:Q9Y223substrate ofInferred only11 paths11 endpoints
- GALEProteinUNIPROT:Q14376substrate ofInferred only10 paths10 endpoints
- POMGNT1ProteinUNIPROT:Q8WZA1substrate ofInferred only10 paths10 endpoints
- SLC35D1ProteinUNIPROT:Q9NTN3transported byInferred only10 paths5 endpoints
- RFNGProteinUNIPROT:Q9Y644substrate ofInferred only10 paths5 endpoints
- B3GNT6ProteinUNIPROT:Q6ZMB0substrate ofInferred only8 paths4 endpoints
- EXTL1ProteinUNIPROT:Q92935substrate ofInferred only8 paths8 endpoints
- B3GNT2ProteinUNIPROT:Q9NY97substrate ofInferred only8 paths8 endpoints
- SLC35A3ProteinUNIPROT:Q9Y2D2transported byInferred only8 paths8 endpoints
- GCNT4ProteinUNIPROT:Q9P109substrate ofInferred only8 paths4 endpoints
- ENPP3ProteinUNIPROT:O14638substrate ofInferred only7 paths7 endpoints
- SLC35D4ProteinUNIPROT:Q24JQ0transported byInferred only6 paths6 endpoints
- B3GNT4ProteinUNIPROT:Q9C0J1substrate ofInferred only6 paths6 endpoints
- POMGNT2ProteinUNIPROT:Q8NAT1substrate ofInferred only5 paths5 endpoints
- HAS1ProteinUNIPROT:Q92839substrate ofInferred only5 paths5 endpoints
- HAS3ProteinUNIPROT:O00219substrate ofInferred only5 paths5 endpoints
- PIGAProteinUNIPROT:P37287substrate ofInferred only5 paths5 endpoints
- SLC35D2ProteinUNIPROT:Q76EJ3transported byInferred only4 paths4 endpoints
- HAS2ProteinUNIPROT:Q92819substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
93 statements
93 statements · 1 reference database · Subject: UDP-N-acetyl-alpha-D-glucosamine · Sources: Rhea
- UDP-N-acetyl-alpha-D-glucosamine is converted to aldehydo-N-acetyl-D-mannosamineCompoundRhea RHEA:30683Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is converted to N-acetyl-alpha-D-glucosamine 1-phosphateCompoundRhea RHEA:29547Inferred only
- N-acetyl-alpha-D-glucosamine 1-phosphate is converted to UDP-N-acetyl-alpha-D-glucosamineCompoundRhea RHEA:13509Inferred only
- UDP-N-acetyl-alpha-D-galactosamine is converted to UDP-N-acetyl-alpha-D-glucosamineCompoundRhea RHEA:20517Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is converted to UDP-N-acetyl-alpha-D-galactosamineCompoundRhea RHEA:20517Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of A4GNTProteinRhea RHEA:86039Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of A4GNTProteinRhea RHEA:86059Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of A4GNTProteinRhea RHEA:86035Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of A4GNTProteinRhea RHEA:85983Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of A4GNTProteinRhea RHEA:86043Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of ALG13ProteinRhea RHEA:23380Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT2ProteinRhea RHEA:14389Inferred only
Show the remaining 81
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT3ProteinRhea RHEA:56224Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT3ProteinRhea RHEA:14389Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT3ProteinRhea RHEA:56220Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT4ProteinRhea RHEA:14389Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT5ProteinRhea RHEA:13905Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT5ProteinRhea RHEA:23004Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT6ProteinRhea RHEA:46884Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT6ProteinRhea RHEA:46880Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of B3GNT8ProteinRhea RHEA:14389Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of DPAGT1ProteinRhea RHEA:13289Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of ENPP3ProteinRhea RHEA:29547Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EOGTProteinRhea RHEA:48904Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EOGTProteinRhea RHEA:48908Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EXT2ProteinRhea RHEA:16213Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EXTL1ProteinRhea RHEA:16213Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EXTL2ProteinRhea RHEA:16221Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of EXTL3ProteinRhea RHEA:16221Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GALEProteinRhea RHEA:20517Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT1ProteinRhea RHEA:56216Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT1ProteinRhea RHEA:69691Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT1ProteinRhea RHEA:56900Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT1ProteinRhea RHEA:56212Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT2ProteinRhea RHEA:54820Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT3ProteinRhea RHEA:56212Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT3ProteinRhea RHEA:56216Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT3ProteinRhea RHEA:54820Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT3ProteinRhea RHEA:56188Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT3ProteinRhea RHEA:56192Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT4ProteinRhea RHEA:56216Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GCNT4ProteinRhea RHEA:56212Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GNEProteinRhea RHEA:30683Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of GNPTABProteinRhea RHEA:13581Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of HAS1ProteinRhea RHEA:20465Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of HAS2ProteinRhea RHEA:20465Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of HAS3ProteinRhea RHEA:20465Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of LFNGProteinRhea RHEA:70531Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of LFNGProteinRhea RHEA:70511Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MFNGProteinRhea RHEA:70531Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MFNGProteinRhea RHEA:70511Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT1ProteinRhea RHEA:11456Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT1ProteinRhea RHEA:84123Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT2ProteinRhea RHEA:12941Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT3ProteinRhea RHEA:15509Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT3ProteinRhea RHEA:83967Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT3ProteinRhea RHEA:85375Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69615Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69627Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69619Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69631Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69623Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:69635Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4AProteinRhea RHEA:16057Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69635Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69619Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69623Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69627Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69631Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:16057Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4BProteinRhea RHEA:69615Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT4CProteinRhea RHEA:16057Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT5ProteinRhea RHEA:16921Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT5BProteinRhea RHEA:56256Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT5BProteinRhea RHEA:56252Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of MGAT5BProteinRhea RHEA:16921Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of OGTProteinRhea RHEA:48908Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of OGTProteinRhea RHEA:48904Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of PIGAProteinRhea RHEA:14789Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of POMGNT1ProteinRhea RHEA:54128Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of POMGNT2ProteinRhea RHEA:37663Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of RFNGProteinRhea RHEA:70511Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is a substrate of RFNGProteinRhea RHEA:70531Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35A2ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35A2ProteinRhea RHEA:74611Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35A3ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35A5ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35B4ProteinRhea RHEA:73703Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35D1ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35D1ProteinRhea RHEA:73703Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35D2ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35D4ProteinRhea RHEA:72695Inferred only
- UDP-N-acetyl-alpha-D-glucosamine is transported by SLC35G3ProteinRhea RHEA:72695Inferred only
Reactions
102 reactions
N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)+UDP-N-acetyl-alpha-D-glucosamineN(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+UDP+hydron
Catalysed by MGAT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:11456CC BY 4.0Reference data
an N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+UDP-N-acetyl-alpha-D-glucosamineN(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein]+UDP+hydron
Catalysed by MGAT2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:12941CC BY 4.0Reference data
a di-trans,poly-cis-dolichyl phosphate+UDP-N-acetyl-alpha-D-glucosaminean N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol+UMP
Catalysed by DPAGT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:13289CC BY 4.0Reference data
UDP-N-acetyl-alpha-D-glucosamine+2NAD(1-)+waterCHEBI:65040+2NADH(2-)+3hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13325CC BY 4.0Reference data
N-acetyl-alpha-D-glucosamine 1-phosphate+UTP+hydronUDP-N-acetyl-alpha-D-glucosamine+diphosphate(3-)
Catalysed by UAP1
Reaction pageLeft to rightBalanced
Rhea RHEA:13509CC BY 4.0Reference data
N(4)-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein]+UDP-N-acetyl-alpha-D-glucosamineN(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein]+UMP+hydron
Catalysed by GNPTAB
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13581CC BY 4.0Reference data
CHEBI:17631+UDP-N-acetyl-alpha-D-glucosamineCHEBI:29111+UDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13705CC BY 4.0Reference data
a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP-N-acetyl-alpha-D-glucosaminea beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))+UDP+hydron
Catalysed by B3GNT5
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:13905CC BY 4.0Reference data
(3R)-hydroxytetradecanoyl-[ACP]+UDP-N-acetyl-alpha-D-glucosamineCHEBI:61494+holo-[ACP]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13925CC BY 4.0Reference data
17alpha-estradiol 3-O-(beta-D-glucuronate)+UDP-N-acetyl-alpha-D-glucosamineCHEBI:73194+UDP+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14153CC BY 4.0Reference data
a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative+UDP-N-acetyl-alpha-D-glucosaminean N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative+UDP+hydron
Catalysed by B3GNT8 or B3GNT4 or B3GNT2 or B3GNT3
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:14389CC BY 4.0Reference data
a di-trans,poly-cis-dolichyl phosphate+UDP-N-acetyl-alpha-D-glucosaminean N-acetyl-alpha-D-glucosaminyl-phospho-di-trans,poly-cis-dolichol+UDP
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:14693CC BY 4.0Reference data
Where it reaches
7 systems, 10 regions, 18 tissues, 23 transporter routes — routes, not measurements: transporters known to carry UDP-N-acetyl-alpha-D-glucosamine are expressed there, and no source reports it arriving.
Loading the model…
Other names
4 names
Resolves to: UDP-N-acetyl-alpha-D-glucosamine
- Also called
- UDP-N-acetyl-alpha-D-glucosamine dianionUDP-N-acetyl-α-D-glucosamine dianion
- Systematic name
- uridine 5'-[3-(acetamido-2-deoxy-alpha-D-glucopyranosyl) diphosphate]uridine 5'-[3-(acetamido-2-deoxy-α-D-glucopyranosyl) diphosphate]