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Reference

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D-galactose

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

6 compounds within 3 steps: 2 in 1, 1 in 2, 3 in 3

Does it reach a compound?

One step

D-galactono-1,5-lactoneReach from here →
1. D-galactose + NADP(+) = D-galactono-1,5-lactone + NADPH + H(+)
Catalysed by DHDH
galactitolReach from here →
1. galactitol + NADP(+) = D-galactose + NADPH + H(+)
Catalysed by AKR1B1

Two steps

alpha-D-galactoseReach from here →
1. galactitol + NADP(+) = D-galactose + NADPH + H(+)
2. galactitol:NADP+ 1-oxidoreductase
Catalysed by AKR1B1cytosol

Three steps

a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))Reach from here →
Catalysed by AKR1B1, LCT, GLB1, GLB1Lcytosol, extracellular space
beta-D-galactoseReach from here →
Catalysed by

cytosol, nucleus

One of 2 routes

alpha-D-galactose 1-phosphateReach from here →

galactitol + NADP(+) = D-galactose + NADPH + H(+)
galactitol:NADP+ 1-oxidoreductase
galactokinase (galactose)

Catalysed by AKR1B1, GALK1, GALK2cytosolOne of 2 routes