What the reference databases state

Statements

30 statements

30 statements · 7 reference databases · Subject: GAD2 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, UniProt, WikiPathways

Order

GAD2 is expressed in caudate nucleusAnatomyHuman Protein Atlas ENSG00000136750Inferred only
GAD2 is expressed in cerebellumAnatomyHuman Protein Atlas ENSG00000136750Inferred only
GAD2 is expressed in cerebral cortexAnatomyHuman Protein Atlas ENSG00000136750Inferred only
GAD2 is expressed in islet of LangerhansAnatomyBgee ENSG00000136750Inferred only
GAD2 is expressed in nucleus accumbensAnatomyBgee ENSG00000136750Inferred only
GAD2 is expressed in pancreasAnatomyHuman Protein Atlas ENSG00000136750Inferred only
GAD2 is expressed in putamenAnatomyBgee ENSG00000136750Inferred only
GAD2 is expressed in type B pancreatic cellCell typeBgee ENSG00000136750Inferred only
F10 interacts with GAD2ProteinHetionet hetionet:interacts:2159-2572Inferred only
GAD1 interacts with GAD2ProteinHetionet hetionet:interacts:2571-2572Inferred only
GAD2 interacts with PRKACAProteinHetionet hetionet:interacts:2572-5566Inferred only
GAD2 interacts with PRKCEProteinHetionet hetionet:interacts:2572-5581Inferred only

Show the remaining 18

GAD2 participates in Alanine and aspartate metabolismPathwayWikiPathways WP106Inferred only
GAD2 participates in Biogenic amine synthesisPathwayWikiPathways WP550Inferred only
GAD2 participates in Cell lineage map for neuronal differentiationPathwayWikiPathways WP5417Inferred only
GAD2 participates in GABA metabolism aka GHB PathwayWikiPathways WP4157Inferred only
GAD2 participates in GABA receptor signalingPathwayWikiPathways WP4159Inferred only
GAD2 participates in GABA synthesisPathwayReactome R-HSA-888568Inferred only
GAD2 participates in GABA synthesis, release, reuptake and degradationPathwayReactome R-HSA-888590Inferred only
GAD2 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
GAD2 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
GAD2 participates in MECP2 regulates transcription of genes involved in GABA signalingPathwayReactome R-HSA-9022927Inferred only
GAD2 participates in Neuronal SystemPathwayReactome R-HSA-112316Inferred only
GAD2 participates in Neurotransmitter release cyclePathwayReactome R-HSA-112310Inferred only
GAD2 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
GAD2 participates in Trans sulfuration one carbon metabolism and related pathwaysPathwayWikiPathways WP2525Inferred only
GAD2 participates in Transcriptional Regulation by MECP2PathwayReactome R-HSA-8986944Inferred only
GAD2 participates in Transmission across Chemical SynapsesPathwayReactome R-HSA-112315Inferred only
GAD2 requires the cofactor pyridoxal 5'-phosphateCompoundUniProt Q05329Inferred only
L-aspartate is a substrate of GAD2CompoundHuman-GEM MAR04174Inferred only

Reactions

3 reactions

L-aspartate+protonbeta-alanine+carbon dioxide
Catalysed by GAD2
Reaction pageLeft to rightBalancedEC 4.1.1.11, 4.1.1.15cytosol
Human-GEM MAR04174CC BY 4.0Reference data
L-glutamate(1-)+proton4-aminobutanoate+carbon dioxide
Catalysed by GAD1 or GAD2
Reaction pageLeft to rightBalancedEC 4.1.1.15

Other names

4 names

Resolves to: GAD2

Also called: 65 kDa glutamic acid decarboxylaseGAD-65GAD65Glutamate decarboxylase 65 kDa isoform