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Proteins/UNIPROT:P45381
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it acts as a scavenger of NAA from body fluids..
Function from UniProtKB (P45381), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
20 statements
20 statements · 8 reference databases · Subject: ASPA · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
4 reactions
water+MAM02531cacetate+L-asparagine
Reaction pageReversibleBalancedEC 3.5.1.15cytosol
Human-GEM MAR06969CC BY 4.0Reference data
water+N-acetyl-L-aspartateacetate+L-aspartate
Reaction pageLeft to rightBalanced
4 names
Resolves to: ASPA
Human-GEM MAR08628CC BY 4.0Reference data
an N-acyl-L-aspartate+watera carboxylate+L-aspartate
Catalysed by ASPA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:10872CC BY 4.0Reference data
N-acetyl-L-aspartate+waterL-aspartate+acetate
Catalysed by ASPA
Reaction pageLeft to rightBalanced
Rhea RHEA:59408CC BY 4.0Reference data