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Proteins/UNIPROT:Q9UBQ7
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate..
Function from UniProtKB (Q9UBQ7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
160 statements
160 statements · 7 reference databases · Subject: GRHPR · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
8 reactions
proton+3-hydroxypyruvic acid+NADPH(4-)(R)-glycerate+NADP(3-)
Catalysed by GRHPR
Reaction pageLeft to rightBalancedEC 1.1.1.79, 1.1.1.81cytosol
Human-GEM MAR04465CC BY 4.0Reference data
glyoxylic acid+proton+NADPH(4-)glycolate+NADP(3-)
Catalysed by GRHPR
1 name
Resolves to: GRHPR
Human-GEM MAR07702CC BY 4.0Reference data
proton+methylglyoxal+NADPH(4-)(R)-lactaldehyde+NADP(3-)
Catalysed by GRHPR
Reaction pageLeft to rightBalancedEC 1.1.1.79, 1.1.1.81cytosol
Human-GEM MAR08501CC BY 4.0Reference data
glyoxylic acid+proton+NADPH(4-)glycolate+NADP(3-)
Catalysed by GRHPR
Reaction pageLeft to rightBalancedEC 1.1.1.79mitochondrial matrix
Human-GEM MAR08779CC BY 4.0Reference data
proton+3-hydroxypyruvic acid+NADH(2-)(R)-glycerate+NAD(+)
Catalysed by GRHPR
Reaction pageLeft to rightBalancedEC 1.1.1.79, 1.1.1.81cytosol
Human-GEM MAR08782CC BY 4.0Reference data
glycolate+NADP(3-)glyoxylate+NADPH(4-)+hydron
Catalysed by GRHPR
Reaction pageDirection not assertedBalanced
Rhea RHEA:10992CC BY 4.0Reference data
(R)-glycerate+NAD(1-)3-hydroxypyruvate+NADH(2-)+hydron
Catalysed by GRHPR
Reaction pageDirection not assertedBalanced
Rhea RHEA:17905CC BY 4.0Reference data
(R)-glycerate+NADP(3-)3-hydroxypyruvate+NADPH(4-)+hydron
Catalysed by GRHPR
Reaction pageDirection not assertedBalanced
Rhea RHEA:18657CC BY 4.0Reference data