CHEBI:15570
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
603 compounds within 3 steps: 5 in 1, 139 in 2, 459 in 3
Two steps
Catalysed by GGT1, GGT5, GGTLC2, GGT6 and 2 morecytosol, extracellular space
- transport of D-alanine and glycine (cytosol to extracellular)
- dihydrolipoyl dehydrogenase ([protein]-N6-(lipoyl)lysine)
Catalysed by SLC3A2, SLC7A10, GLDC, GCSHextracellular space, cytosol, mitochondrial matrix
Catalysed by SLC7A10cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
- transport of D-alanine and glycine (cytosol to extracellular)
- sarcosine + O2 + H2O = formaldehyde + glycine + H2O2
Catalysed by SLC3A2, SLC7A10, PIPOXextracellular space, cytosolOne of 2 routes
- transport of D-alanine and glycine (cytosol to extracellular)
- (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Catalysed by SLC3A2, SLC7A10, SHMT1, SHMT2extracellular space, cytosol
- transport of D-alanine and glycine (cytosol to extracellular)
- an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL3, GLYAT and 1 moreextracellular space, cytosol
Catalysed by SLC3A2, SLC7A10, GATMextracellular space, cytosolOne of 2 routes
Catalysed by SLC7A10cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
Catalysed by SLC7A5cytosol, extracellular spaceOne of 20 routes
Catalysed by SLC7A5cytosol, extracellular spaceOne of 13 routes
- transport of D-alanine and glycine (cytosol to extracellular)
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
Catalysed by SLC3A2, SLC7A10, GSSextracellular space, cytosol
Catalysed by SLC7A10cytosol, inner side of the membrane, outer side of the membraneOne of 8 routes
Catalysed by KYNUcytosol
Catalysed by SLC7A10cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
Catalysed by SLC7A5cytosol, extracellular spaceOne of 20 routes
Catalysed by SLC7A5cytosol, extracellular spaceOne of 20 routes
Catalysed by KYNUcytosol
- transport of D-alanine and glutamine (cytosol to extracellular)
- HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
Catalysed by SLC3A2, SLC7A10, CADextracellular space, cytosolOne of 2 routes
- transport of D-alanine and glycine (cytosol to extracellular)
- L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine
Catalysed by SLC3A2, SLC7A10, AADATextracellular space, cytosol
- alanine racemase
- N(omega),N(omega)-dimethyl-L-arginine + pyruvate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine
Catalysed by AGXT2cytosolOne of 2 routes
- alanine racemase
- trans-4-hydroxy-L-proline(out) + L-alanine(in) + Na(+)(out) = trans-4-hydroxy-L-proline(in) + L-alanine(out) + Na(+)(in)
Catalysed by SLC1A4cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
- transport of D-alanine and glutamine (cytosol to extracellular)
- phosphoribosyl pyrophosphate amidotransferase (glutamine)
Catalysed by SLC3A2, SLC7A10, PPATextracellular space, cytosolOne of 2 routes
- transport of D-alanine and glutamine (cytosol to extracellular)
- D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Catalysed by SLC3A2, SLC7A10, GFPT2, GFPT1extracellular space, cytosol
- transport of D-alanine and glycine (cytosol to extracellular)
- (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine = N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL2extracellular space, cytosolOne of 2 routes
- alanine racemase
- L-proline(out) + L-alanine(in) + Na(+)(out) = L-proline(in) + L-alanine(out) + Na(+)(in)
Catalysed by SLC1A4cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes
Catalysed by SLC3A2, SLC7A10extracellular space, cytosol, mitochondrial matrixOne of 2 routes
Catalysed by GGTLC3, GGT1, GGT5, GGTLC2 and 2 morecytosolOne of 2 routes
Catalysed by MOCOScytosol
Catalysed by AGXT2cytosolOne of 2 routes
Catalysed by SLC3A2, SLC7A10extracellular space, cytosolOne of 2 routes
- transport of D-alanine and glycine (cytosol to extracellular)
- tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL2extracellular space, cytosol
- transport of D-alanine and glycine (cytosol to extracellular)
- eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-alanine and glycine (cytosol to extracellular)
- docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-alanine and glycine (cytosol to extracellular)
- hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, BAATextracellular space, cytosol
- transport of D-alanine and glutamine (cytosol to extracellular)
- an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by SLC3A2, SLC7A10, GLYATL1B, GLYATL1extracellular space, cytosol
- D-alanine:oxygen oxidoreductase (deaminating)
- pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)
Catalysed by DAO, PDHA1, PDHB, PDHA2peroxisome, mitochondrial matrix
Three steps
- alanine racemase
- transport of alanine and tryptophan (cytosol to extracellular)
- beta-carboline hydrolysis
Catalysed by SLC7A5cytosol, extracellular space
- D-alanine:oxygen oxidoreductase (deaminating)
- transport of acetoacetate and pyruvate (cytosol to mitochondria)
- (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate
Catalysed by DAO, ADHFE1peroxisome, mitochondrial matrix, cytosol