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Proteins/UNIPROT:Q16719
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity..
Function from UniProtKB (Q16719), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
77 statements
77 statements · 8 reference databases · Subject: KYNU · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
5 reactions
water+CHEBI:30249L-alanine+N-formylanthranilic acid+proton
Catalysed by KYNU
Reaction pageLeft to rightBalancedEC 3.7.1.3cytosol
Human-GEM MAR04218CC BY 4.0Reference data
water+L-kynurenineL-alanine+anthranilic acid+proton
Catalysed by KYNU
1 name
Resolves to: KYNU
Human-GEM MAR04224CC BY 4.0Reference data
CHEBI:17380+water3-hydroxyanthranilic acid+L-alanine
Catalysed by KYNU
Reaction pageLeft to rightBalancedEC 3.7.1.3cytosol
Human-GEM MAR04225CC BY 4.0Reference data
L-kynurenine+wateranthranilate+L-alanine+hydron
Catalysed by KYNU
Reaction pageDirection not assertedBalanced
Rhea RHEA:16813CC BY 4.0Reference data
3-hydroxy-L-kynurenine+water3-hydroxyanthranilate+L-alanine+hydron
Catalysed by KYNU
Reaction pageDirection not assertedBalanced
Rhea RHEA:25143CC BY 4.0Reference data