Compound
guanidinoacetate
Zwitterionic form of guanidinoacetic acid having an anionic carboxy group and a protonated guanidino group; major species at pH 7.3.
Definition from ChEBI (CHEBI:57742), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C3H7N3O2
- Mass
- 117.108 g/mol
- Charge
- 0
- InChIKey
- BPMFZUMJYQTVII-UHFFFAOYSA-N
- SMILES
- NC(=[NH2+])NCC(=O)[O-]
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
0 reported hops3 assembled from the scaffold
- creatineCompoundCHEBI:16919converted toInferred only68 paths19 endpoints
- GAMTProteinUNIPROT:Q14353substrate ofInferred only30 paths15 endpoints
- GATMProteinUNIPROT:P50440substrate ofInferred only8 paths8 endpoints
What the reference databases state
Statements
8 statements
8 statements · 2 reference databases · Subject: guanidinoacetate · Sources: Human-GEM, Rhea
- creatine is converted to guanidinoacetateCompoundRhea RHEA:10656Inferred only
- guanidinoacetate is converted to creatineCompoundHuman-GEM MAR04583Inferred only
- guanidinoacetate is converted to creatineCompoundRhea RHEA:10656Inferred only
- creatine is converted to guanidinoacetateCompoundHuman-GEM MAR04583Inferred only
- guanidinoacetate is a substrate of GAMTProteinHuman-GEM MAR04583Inferred only
- guanidinoacetate is a substrate of GAMTProteinRhea RHEA:10656Inferred only
- guanidinoacetate is a substrate of GATMProteinHuman-GEM MAR04582Inferred only
- guanidinoacetate is transported by SLC16A12ProteinRhea RHEA:73047Inferred only
Reactions
10 reactions
L-arginine+glycineguanidinoacetate+L-ornithine
Catalysed by GATM
Reaction pageReversibleBalancedEC 2.1.4.1cytosol
Human-GEM MAR04582CC BY 4.0Reference data
creatine+proton+CHEBI:16680guanidinoacetate+S-adenosyl-L-methionine
Catalysed by GAMT
Reaction pageReversibleBalancedEC 2.1.1.2cytosol
Human-GEM MAR04583CC BY 4.0Reference data
chlorine(.)+guanidinoacetate+2sodium(1+)chlorine(.)+guanidinoacetate+2sodium(1+)
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR09170CC BY 4.0Reference data
guanidinoacetateguanidinoacetate
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR09186CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09852CC BY 4.0Reference data
guanidinoacetate+S-adenosyl-L-methioninecreatine+S-adenosyl-L-homocysteine+hydron
Catalysed by GAMT
Reaction pageDirection not assertedBalanced
Rhea RHEA:10656CC BY 4.0Reference data
L-arginine+glycineguanidinoacetate+L-ornithine
Catalysed by GATM
Reaction pageLeft to rightBalanced
Rhea RHEA:13201CC BY 4.0Reference data
guanidinoacetate+ATP(4-)CHEBI:57612+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14145CC BY 4.0Reference data
guanidinoacetate+waterurea+glycine
Reaction pageDirection not assertedBalanced
Rhea RHEA:23268CC BY 4.0Reference data
guanidinoacetateguanidinoacetate
Transported by SLC16A12
Reaction pageDirection not assertedBalanced
Rhea RHEA:73047CC BY 4.0Reference data
On the label
Labelled products
21 products
Source: NIH DSLD · Ingredient: guanidinoacetate · 21 products · Declared amount per serving: 35–500 mg (16 products)
16 labels state an amount5 do not
- GNC AMPMass XXX Chocolate500 mgper 205 Gram(s)DSLD:210519
- GNC AMP Advanced Muscle PerformanceMass XXX Chocolate Raspberry Truffle500 mgper 205 Gram(s)DSLD:221476
- GNC AMP Advanced Muscle PerformanceMass XXX Cookies & Cream500 mgper 205 Gram(s)DSLD:221370
- GNC AMP Advanced Muscle PerformanceMass XXX Strawberry500 mgper 205 Gram(s)DSLD:229547
- GNC AMP Advanced Muscle PerformanceMass XXX Vanilla500 mgper 205 Gram(s)DSLD:221167
- GNC Pro PerformanceCreatine Advance XR Unflavoredamount not statedper 7 Gram(s)DSLD:74586
- GNC Pro Performance AMPAmplified Creatine XXX Power Fruit Punch250 mgper 8.39 Gram(s)DSLD:69334
- GNC Pro Performance AMPAmplified Creatine XXX Power Fruit Punch125 mgper 8.39 Gram(s)DSLD:69334
- GNC Pro Performance AMPAmplified Creatine XXX Power Orange Twist125 mgper 8.42 Gram(s)DSLD:49630
- GNC Pro Performance AMPAmplified Creatine XXX Power Orange Twist250 mgper 8.42 Gram(s)DSLD:49630
- GNC Pro Performance AMPAmplified Creatine XXX Ripped Fruit Punch125 mgper 9.73 Gram(s)DSLD:33608
- GNC Pro Performance AMPAmplified Creatine XXX Ripped Fruit Punch250 mgper 9.73 Gram(s)DSLD:33608
Show the remaining 9
- GNC Pro Performance AMPAmplified Creatine XXX Ripped Orange Twist125 mgper 9.59 Gram(s)DSLD:49626
- GNC Pro Performance AMPAmplified Creatine XXX Ripped Orange Twist250 mgper 9.59 Gram(s)DSLD:49626
- GNC Pro Performance AMPAmplified Mass XXX Chocolateamount not statedper 205 Gram(s)DSLD:175429
- GNC Pro Performance AMPAmplified Mass XXX Vanillaamount not statedper 205 Gram(s)DSLD:75181
- GNC Pro Performance AMPAmplified N.O. Loaded V2 Blue Raspberry70 mgper 11.4 Gram(s)DSLD:74603
- GNC Pro Performance AMPAmplified N.O. Loaded V2 Fruit Punch70 mgper 11 Gram(s)DSLD:27346
- GNC Pro Performance AMPAmplified N.O. Loaded V2 Watermelon35 mgper 11.3 Gram(s)DSLD:27343
- GNC Pro Performance AMP Advanced Muscle PerformanceAmplified N.O. Loaded Blue Raspberryamount not statedper 21 Gram(s)DSLD:5861
- GNC Pro Performance AMP Advanced Muscle PerformanceAmplified N.O. Loaded Fruit Punchamount not statedper 22 Gram(s)DSLD:4290
Label record: NIH Office of Dietary Supplements · CC0
Other names
1 name
Resolves to: guanidinoacetate
- Systematic name
- 2-{[amino(iminiumyl)methyl]amino}acetate