Compound
(6S)-5,6,7,8-tetrahydrofolate
No description recorded for this entry yet. Everything this graph holds about (6S)-5,6,7,8-tetrahydrofolate is below.
Structure
No depiction stored for this entry. The InChIKey and SMILES beside this define the structure exactly.
- Class
- Organic compound, anion
- Formula
- C19H21N7O6
- Mass
- 443.42 g/mol
- Charge
- -2
- InChIKey
- MSTNYGQPCMXVAQ-RYUDHWBXSA-L
- SMILES
- Nc1nc2c(c(=O)n1)N[C@@H](CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1)CN2
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence — none of it carries a grade.
What it touches on the way
A finding says (6S)-5,6,7,8-tetrahydrofolate moved an endpoint. This is the biology in between: the proteins and reactions it runs through to get there. It is where to look for the two things a list of findings cannot answer — why a result might happen, and what else acts on the same machinery.
15 of these are proteins with a page of their own, and that is the door: a protein page says what else it carries, which is how one compound leads to the next.
Mechanistic reach
15 entities
15 entities reached, most connected first. Hub metabolites are excluded, so this is not a claim that the compound touches everything.
0 reported hops15 assembled from the scaffold
- MTRProteinUNIPROT:Q99707substrate ofInferred only36 paths36 endpoints
- SHMT2ProteinUNIPROT:P34897substrate ofInferred only22 paths22 endpoints
- DHFRProteinUNIPROT:P00374substrate ofInferred only21 paths21 endpoints
- SHMT1ProteinUNIPROT:P34896substrate ofInferred only19 paths19 endpoints
- ATICProteinUNIPROT:P31939substrate ofInferred only12 paths12 endpoints
- MTHFD1ProteinUNIPROT:P11586substrate ofInferred only10 paths10 endpoints
- ALDH1L1ProteinUNIPROT:O75891metabolized byInferred only8 paths8 endpoints
- GARTProteinUNIPROT:P22102substrate ofInferred only8 paths8 endpoints
- AMTProteinUNIPROT:P48728substrate ofInferred only8 paths8 endpoints
- FTCDProteinUNIPROT:O95954substrate ofInferred only7 paths7 endpoints
- MTHFD1LProteinUNIPROT:Q6UB35substrate ofInferred only6 paths6 endpoints
- ALDH1L2ProteinUNIPROT:Q3SY69metabolized byInferred only5 paths5 endpoints
What the reference databases state
The section above shows paths a projection assembled. This is the reference layer itself, one step from (6S)-5,6,7,8-tetrahydrofolate: what the cleared databases state it reacts with, is carried by, is converted to and takes part in, whether or not a projection has walked it yet.
Statements
19 statements
19 statements in 1 reference database name (6S)-5,6,7,8-tetrahydrofolate — Rhea. Press a relation to see only its rows; every count is the rows behind it.
- (6R)-10-formyltetrahydrofolate is converted to (6S)-5,6,7,8-tetrahydrofolateCompoundRhea RHEA:10180Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is converted to (6R)-10-formyltetrahydrofolateCompoundRhea RHEA:10180Inferred only
- 7,8-dihydrofolate is converted to (6S)-5,6,7,8-tetrahydrofolateCompoundRhea RHEA:15009Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is converted to 7,8-dihydrofolateCompoundRhea RHEA:15009Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is metabolised by ALDH1L1ProteinRhea RHEA:10180Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is metabolised by ALDH1L2ProteinRhea RHEA:10180Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of AMTProteinRhea RHEA:16945Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of ATICProteinRhea RHEA:22192Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of DHFRProteinRhea RHEA:15009Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of DHFR2ProteinRhea RHEA:15009Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of FTCDProteinRhea RHEA:15097Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of GARTProteinRhea RHEA:15053Inferred only
Show the remaining 7
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of GGHProteinRhea RHEA:56784Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of MTFMTProteinRhea RHEA:24380Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of MTHFD1ProteinRhea RHEA:20221Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of MTHFD1LProteinRhea RHEA:20221Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of MTRProteinRhea RHEA:11172Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of SHMT1ProteinRhea RHEA:15481Inferred only
- (6S)-5,6,7,8-tetrahydrofolate is a substrate of SHMT2ProteinRhea RHEA:15481Inferred only
Other names
2 names
Every name this graph resolves to (6S)-5,6,7,8-tetrahydrofolate. Searching any of them lands here.
- Also called
- (6S)-5,6,7,8-tetrahydrofolate dianion
- Systematic name
- N-[4-({[(6S)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate