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Proteins/UNIPROT:Q96N66
Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell. In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation..
Function from UniProtKB (Q96N66), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
351 statements
351 statements · 6 reference databases · Subject: MBOAT7 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea · Rows fetched: 300
5 reactions
CHEBI:1146900+proton+MAM02538cCHEBI:15351+CHEBI:15650
Catalysed by LPCAT2 or NAT14 or SH3GLB1 or ZDHHC8 or NAA10 or ZDHHC15 or ZDHHC2 or NAT9 or NAA40 or LPCAT3 or NAA60 or MBOAT7 and 20 more alternatives
14 names
Resolves to: MBOAT7
Human-GEM MAR01088CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)+an acyl-CoAa 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)+coenzyme A(4-)
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:33195CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Reaction pageLeft to rightBalanced
Rhea RHEA:35999CC BY 4.0Reference data
1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)+(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)+coenzyme A(4-)
Catalysed by MBOAT7
Reaction pageLeft to rightBalanced
Rhea RHEA:36835CC BY 4.0Reference data
a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)+(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoAa 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)+coenzyme A(4-)
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:37015CC BY 4.0Reference data