Proteins/UNIPROT:Q13308

PTK7

ProteinUNIPROT:Q13308

Inactive tyrosine kinase involved in the Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathways. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Does not bind ATP..

Function from UniProtKB (Q13308), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

34 statements

34 statements · 2 reference databases · Subject: PTK7 · Sources: gene ontology, Hetionet

Order

PTK7 covaries with KRTAP24-1ProteinHetionet hetionet:covaries:5754-643803Inferred only
OR2B2 covaries with PTK7ProteinHetionet hetionet:covaries:5754-81697Inferred only
PARG covaries with PTK7ProteinHetionet hetionet:covaries:5754-8505Inferred only
SAMD9 covaries with PTK7ProteinHetionet hetionet:covaries:54809-5754Inferred only
CTNNB1 interacts with PTK7ProteinHetionet hetionet:interacts:1499-5754Inferred only
PTK7 interacts with UBCProteinHetionet hetionet:interacts:5754-7316Inferred only
PTK7 regulates positive regulation of canonical Wnt signaling pathwayBiological processgene ontology Q13308|GO:0090263Inferred only
PTK7 regulates positive regulation of neuron projection developmentBiological processgene ontology Q13308|GO:0010976Inferred only
PTK7 regulates regulation of canonical Wnt signaling pathwayBiological processgene ontology Q13308|GO:0060828Inferred only
PTK7 increases the expression of ABCC5ProteinHetionet hetionet:regulates:5754-10057Inferred only
PTK7 increases the expression of COBLProteinHetionet hetionet:regulates:5754-23242Inferred only
PTK7 increases the expression of CPVLProteinHetionet hetionet:regulates:5754-54504Inferred only

Show the remaining 22

PTK7 decreases the expression of CSRP1ProteinHetionet hetionet:regulates:5754-1465Inferred only
PTK7 increases the expression of FASProteinHetionet hetionet:regulates:5754-355Inferred only
PTK7 increases the expression of FKBP14ProteinHetionet hetionet:regulates:5754-55033Inferred only
PTK7 decreases the expression of H2BC12ProteinHetionet hetionet:regulates:5754-85236Inferred only
PTK7 decreases the expression of H2BC4; H2BC6; H2BC7; H2BC8; H2BC10ProteinHetionet hetionet:regulates:5754-8346Inferred only
PTK7 decreases the expression of H2BC4; H2BC6; H2BC7; H2BC8; H2BC10ProteinHetionet hetionet:regulates:5754-8344Inferred only
PTK7 decreases the expression of HAT1ProteinHetionet hetionet:regulates:5754-8520Inferred only
PTK7 increases the expression of HMOX1ProteinHetionet hetionet:regulates:5754-3162Inferred only
PTK7 increases the expression of HOXC6ProteinHetionet hetionet:regulates:5754-3223Inferred only
PTK7 decreases the expression of HSPB1ProteinHetionet hetionet:regulates:5754-3315Inferred only
PTK7 increases the expression of INPP1ProteinHetionet hetionet:regulates:5754-3628Inferred only
PTK7 increases the expression of KCTD5ProteinHetionet hetionet:regulates:5754-54442Inferred only
PTK7 decreases the expression of MAPK1IP1LProteinHetionet hetionet:regulates:5754-93487Inferred only
PTK7 decreases the expression of MBOAT7ProteinHetionet hetionet:regulates:5754-79143Inferred only
PTK7 decreases the expression of MIFProteinHetionet hetionet:regulates:5754-4282Inferred only
PTK7 increases the expression of PLS1ProteinHetionet hetionet:regulates:5754-5357Inferred only
PTK7 increases the expression of PROS1ProteinHetionet hetionet:regulates:5754-5627Inferred only
PTK7 increases the expression of PRSS23ProteinHetionet hetionet:regulates:5754-11098Inferred only
PTK7 decreases the expression of RPA1ProteinHetionet hetionet:regulates:5754-6117Inferred only
PTK7 increases the expression of SATB1ProteinHetionet hetionet:regulates:5754-6304Inferred only
PTK7 decreases the expression of TMEM109ProteinHetionet hetionet:regulates:5754-79073Inferred only
PTK7 increases the expression of WIF1ProteinHetionet hetionet:regulates:5754-11197Inferred only

Other names

6 names

Resolves to: PTK7

Also called: CCK-4CCK4Colon carcinoma kinase 4Protein-tyrosine kinase 7Pseudo tyrosine kinase receptor 7Tyrosine-protein kinase-like 7

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