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Proteins/UNIPROT:O75879
Catalytic subunit of the mitochondrial Glu-tRNA(Gln) amidotransferase complex GatCAB (Probable). GatCAB allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity). This subunit probably recognizes tRNA(Gln) and mediates the transamidation of misloaded Glu by catalyzing formation of the activated gamma-phospho-intermediate and its subsequent aminolysis using ammonia produced by the gatA subunit (Probable)..
Function from UniProtKB (O75879), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
68 statements
68 statements · 4 reference databases · Subject: GATB · Sources: Bgee, Hetionet, Rhea, UniProt
1 reaction
CHEBI:78520+L-glutamine+ATP(4-)+waterCHEBI:78521+L-glutamate(1-)+ADP(3-)+hydrogenphosphate+hydron
Catalysed by GATC or GATB or QRSL1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17521CC BY 4.0Reference data
6 names
Resolves to: GATB