Compound

1-hexadecanoyl-sn-glycero-3-phosphocholine

A lysophosphatidylcholine 16:0 in which a hexadecanoyl (palmitoyl) group is attached to the glycero moiety at position 1.

Definition from ChEBI (CHEBI:72998), read 2026-09-23. CC BY 4.0.

CHEBI:72998ChEBI

Open in the graph

Structure

2D depiction

No three-dimensional record for this entry.

Class: Organic compound
Formula: C24H50NO7P
Mass: 495.638 g/mol
Charge: 0
InChIKey: ASWBNKHCZGQVJV-HSZRJFAPSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)([O-])OCC[N+](C)(C)C
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

38 entities

38 entities reached.

0 reported hops38 assembled from the scaffold

Show the remaining 26

What the reference databases state

Chemical structure

1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine has the functional parent 1-hexadecanoyl-sn-glycero-3-phosphocholineCompoundChEBI CHEBI:75300Inferred only
1-hexadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine has the functional parent 1-hexadecanoyl-sn-glycero-3-phosphocholineCompoundChEBI CHEBI:75301Inferred only
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine has the functional parent 1-hexadecanoyl-sn-glycero-3-phosphocholineCompoundChEBI CHEBI:75304Inferred only

Statements

70 statements

70 statements · 2 reference databases · Subject: 1-hexadecanoyl-sn-glycero-3-phosphocholine · Sources: Human-GEM, Rhea

Order

1-hexadecanoyl-sn-glycero-3-phosphocholine is converted to 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholineCompoundRhea RHEA:37703Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:41352Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:40899Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ASPGProteinRhea RHEA:40879Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of CELProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ENPP2ProteinRhea RHEA:38975Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ENPP6ProteinRhea RHEA:41119Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of ENPP7ProteinRhea RHEA:41119Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of GDPD1ProteinRhea RHEA:38975Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of GDPD3ProteinRhea RHEA:38975Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of GDPD3ProteinRhea RHEA:40435Inferred only

Show the remaining 58

1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LCATProteinRhea RHEA:53636Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LIPCProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:35991Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37475Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37515Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:35995Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37703Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:43264Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37867Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:35983Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37855Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37859Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT1ProteinRhea RHEA:37863Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT2ProteinRhea RHEA:37703Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT2ProteinRhea RHEA:35991Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:35991Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:35983Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:35987Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:35995Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:35999Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:37207Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LPCAT3ProteinRhea RHEA:37515Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LYPLA1ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of LYPLA2ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of MBOAT1ProteinRhea RHEA:35991Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of MBOAT2ProteinRhea RHEA:35991Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of MBOAT2ProteinRhea RHEA:35995Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of MBOAT2ProteinRhea RHEA:37207Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of MBOAT7ProteinRhea RHEA:35999Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G15ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4AProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4BProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:40879Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:63656Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:40899Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:63788Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:63772Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4CProteinRhea RHEA:63764Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4EProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G4FProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLA2G6ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PLB1ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PNPLA6ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PNPLA7ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PNPLA8ProteinRhea RHEA:40435Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of PRDX6ProteinRhea RHEA:35983Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of SMPD2ProteinRhea RHEA:41119Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of SMPD3ProteinRhea RHEA:41119Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of TAFAZZINProteinRhea RHEA:43816Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is a substrate of TAFAZZINProteinRhea RHEA:68988Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by ABCA1ProteinHuman-GEM MAR11627Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by ABCB4ProteinHuman-GEM MAR11627Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by ATP10AProteinHuman-GEM MAR11627Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by ATP8B1ProteinHuman-GEM MAR11627Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by ATP8B2ProteinHuman-GEM MAR11627Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by MFSD2AProteinRhea RHEA:43864Inferred only
1-hexadecanoyl-sn-glycero-3-phosphocholine is transported by SPNS1ProteinRhea RHEA:74427Inferred only

Reactions

80 reactions

1-hexadecanoyl-sn-glycero-3-phosphocholine
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR10298CC BY 4.0Reference data
ATP+water+1-hexadecanoyl-sn-glycero-3-phosphocholineADP+proton+phosphate(3-)+1-hexadecanoyl-sn-glycero-3-phosphocholine
Transported by ABCB4 or ATP8B1 or ATP8B2 or ABCA1 or ATP10A
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1cytosol, extracellular space
Human-GEM MAR11627CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-sn-glycero-3-phosphocholine
Reaction pageLeft to rightBalancedEC 7.6.2.2, 7.6.2.1extracellular space, cytosol
Human-GEM MAR11677CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine+hexadecanoyl-CoA1,2-dihexadecanoyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by PRDX6 or LPCAT3 or LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:35983CC BY 4.0Reference data
octadecanoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3
Reaction pageLeft to rightBalanced
Rhea RHEA:35987CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine+(9Z)-octadecenoyl-CoA1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3 or MBOAT1 or MBOAT2 or LPCAT2 or LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:35991CC BY 4.0Reference data
(9Z,12Z)-octadecadienoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3 or MBOAT2 or LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:35995CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3 or MBOAT7
Reaction pageLeft to rightBalanced
Rhea RHEA:35999CC BY 4.0Reference data
(9Z)-hexadecenoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3 or MBOAT2
Reaction pageLeft to rightBalanced
Rhea RHEA:37207CC BY 4.0Reference data
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:37475CC BY 4.0Reference data
dodecanoyl-CoA+1-hexadecanoyl-sn-glycero-3-phosphocholine1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT3 or LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:37515CC BY 4.0Reference data
1-hexadecanoyl-sn-glycero-3-phosphocholine+acetyl-CoA1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine+coenzyme A(4-)
Catalysed by LPCAT2 or LPCAT1
Reaction pageLeft to rightBalanced
Rhea RHEA:37703CC BY 4.0Reference data

Show the remaining 68

Where it reaches

10 systems, 25 regions, 90 tissues, 112 transporter routes — routes, not measurements: transporters known to carry 1-hexadecanoyl-sn-glycero-3-phosphocholine are expressed there, and no source reports it arriving.

Loading the model…

Nervous

Endocrine

Respiratory

Cardiovascular

Digestive

Urinary

Reproductive

Blood and immune

Musculoskeletal

Skin and adipose

Other names

30 names

Resolves to: 1-hexadecanoyl-sn-glycero-3-phosphocholine

Also called: (2R)-2-hydroxy-3-(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate1-16:0-lysoPC1-16:0-lysophosphatidylcholine1-hexadecanoyl-2-lysophosphatidylcholine1-palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine1-palmitoyl-2-lysophosphatidylcholine1-palmitoyl-GPC1-palmitoyl-GPC (16:0)1-palmitoyl-phosphatidylcholine1-palmitoyl-sn-glycero-3-phosphocholine1-palmitoylphosphatidylcholine16:0 LYSO-PCGPC(16:0)GPC(16:0/0:0)GPCho 16:0/0:0GPCho(16:0/0:0)LPC 16:0LPC 16:0/0:0LPC(16:0)LPC(16:0/0:0)LyPC(16:0)LyPC(16:0/0:0)LysoPC 16:0/0:0LysoPC(16:0)LysoPC(16:0/0:0)Lysophosphatidylcholine(16:0)lysophosphatidylcholine(16:0/0:0)PC 16:0/0:0PC(16:0/0:0)
Systematic name: (2R)-3-(hexadecanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate