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Proteins/UNIPROT:P51825
Plays an essential role in the activation of transcription elongation from RNA polymerase II promoters, after transcriptional pausing in response to DNA damage. Upon DNA damage, AFF1-mediated transcriptional recovery requires AFF1 poly-ADP-ribosylation by PARP1..
Function from UniProtKB (P51825), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
228 statements
228 statements · 2 reference databases · Subject: AFF1 · Sources: gene ontology, Hetionet
9 names
Resolves to: AFF1